F1000Research (Jul 2019)

Case Report: Penile necrosis associated to paraphimosis with calciphylaxis due to terminal chronic kidney disease [version 1; peer review: 2 approved]

  • J. Antonio Grandez-Urbina,
  • Elizabeth Corrales-Acosta,
  • J. Eduardo Tejeda-Mariaca,
  • Rafael Pichardo-Rodriguez,
  • Herney Garcia-Perdomo

DOI
https://doi.org/10.12688/f1000research.18834.1
Journal volume & issue
Vol. 8

Abstract

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Background: Penile necrosis is a rare condition that may present in patients with diabetes mellitus or chronic kidney disease (CKD). The recommended treatment is controversial. We report a case of penile necrosis in a diabetic patient caused by episode of paraphimosis associated with uremic arteriopathy treated with partial amputation. Clinical Case: A 53-year-old male with a background of arterial hypertension, diabetes mellitus and CKD in hemodialysis. The patient presented with paraphimosis and glans necrosis. An emergency circumcision was carried out. A doppler ultrasound found fluid collection in the left corpus cavernosum, parietal vascular calcifications and vascular insufficiency in the corpus cavernosum that suggested necrosis. A partial amputation of the penis was carried out. After three years of follow-up, the outcome has remained favorable. Conclusions: Penile necrosis is a rare but serious complication of terminal CKD. In these patients, systemic calciphylaxis is usually observed. The main take-away lesson is that a multidisciplinary approach is necessary.