Clinical Case Reports (Jan 2024)

Large tumoral pseudoangiomatous stromal hyperplasia with ER/PR stromal negativity in a 20‐year‐old female: A rare case report

  • Somar Mansour,
  • Seif‐Aldin Abdul Rahman,
  • Ali Kazour,
  • Ibrahim Salama,
  • Hussain Shmayes,
  • Samer Rajab,
  • Rana Issa

DOI
https://doi.org/10.1002/ccr3.8398
Journal volume & issue
Vol. 12, no. 1
pp. n/a – n/a

Abstract

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Key Clinical Message Pseudoangiomatous stromal hyperplasia (PASH) is a rare lesion of the breast stromal tissue with unknown mechanism. Hormonal stimulation of mammary myofibroblasts is the most important theory due to stromal positivity of progesterone receptor (PR) or/and estrogen receptor (ER). We report a case of PASH with stromal PR/ER negativity.

Keywords