Large tumoral pseudoangiomatous stromal hyperplasia with ER/PR stromal negativity in a 20‐year‐old female: A rare case report

Somar Mansour; Seif‐Aldin Abdul Rahman; Ali Kazour; Ibrahim Salama; Hussain Shmayes; Samer Rajab; Rana Issa

doi:10.1002/ccr3.8398

Clinical Case Reports (Jan 2024)

Large tumoral pseudoangiomatous stromal hyperplasia with ER/PR stromal negativity in a 20‐year‐old female: A rare case report

Somar Mansour,
Seif‐Aldin Abdul Rahman,
Ali Kazour,
Ibrahim Salama,
Hussain Shmayes,
Samer Rajab,
Rana Issa

Affiliations

Somar Mansour: Department of Pathology Cancer Research Center, Tishreen University Hospital Latakia Syria
Seif‐Aldin Abdul Rahman: Department of Obstetrics and Gynecology Cancer Research Center, Tishreen University Hospital Latakia Syria
Ali Kazour: Faculty of Medicine Tishreen University Latakia Syria
Ibrahim Salama: Department of Internal Medicine Tishreen University Hospital Latakia Syria
Hussain Shmayes: Faculty of Medicine Tishreen University Latakia Syria
Samer Rajab: Department of General and Thoracic Surgery Tishreen University Hospital Latakia Syria
Rana Issa: Department of Pathology Cancer Research Center, Tishreen University Hospital Latakia Syria

DOI: https://doi.org/10.1002/ccr3.8398
Journal volume & issue: Vol. 12, no. 1
pp. n/a – n/a

Abstract

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Key Clinical Message Pseudoangiomatous stromal hyperplasia (PASH) is a rare lesion of the breast stromal tissue with unknown mechanism. Hormonal stimulation of mammary myofibroblasts is the most important theory due to stromal positivity of progesterone receptor (PR) or/and estrogen receptor (ER). We report a case of PASH with stromal PR/ER negativity.

Published in Clinical Case Reports

ISSN: 2050-0904 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Medicine (General)
Website: https://onlinelibrary.wiley.com/journal/20500904

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Abstract

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