Stem Cell Research (Dec 2019)

Generation of human iPS cell line CBTCi001-A from dermal fibroblasts obtained from a healthy donor

  • Gabriele Louise Soares Martins,
  • Bruno Diaz Paredes,
  • Gabriela Louise de Almeida Sampaio,
  • Carolina Kymie Vasques Nonaka,
  • Katia Nunes da Silva,
  • Kyan James Allahdadi,
  • Luciana Souza de Aragão França,
  • Milena Botelho Pereira Soares,
  • Ricardo Ribeiro dos Santos,
  • Bruno Solano de Freitas Souza

Journal volume & issue
Vol. 41

Abstract

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Human-induced pluripotent stem cell (hiPSC) CBTCi001-A line was generated from a healthy 30-year old male dermal fibroblasts using non-integrative reprogramming method using episomal-based plasmids expressing OCT4, SOX2, KLF4, and MYCL. Characterization of CBTCi001-A was confirmed by the expression of typical markers of pluripotency and differentiation potential in vitro.