Therapeutics and Clinical Risk Management (Jun 2023)
Central Oxygen Venous Saturation and Mortality in Patients Undergoing Coronary Artery Bypass Grafting
Abstract
María A Rodríguez-Scarpetta,1,2 Andrés M Sepúlveda-Tobón,3 Jorge E Daza-Arana,1,2 Heiler Lozada-Ramos,2,4,5 Rodrigo A Álzate-Sánchez3 1Physiotherapy Program, Universidad Santiago de Cali, Santiago de Cali, Colombia; 2Research Group on Health and Movement, Universidad Santiago de Cali, Santiago de Cali, Colombia; 3Master in Epidemiology, Universidad Libre, Santiago de Cali, Colombia; 4Medicine Program, Universidad Santiago de Cali, Palmira, Colombia; 5Doctoral Program in Infectious Diseases, Universidad de Santander, Bucaramanga, ColombiaCorrespondence: María A Rodríguez-Scarpetta, Physiotherapy Program, Universidad Santiago de Cali, Calle 5 # 62-00, Santiago de Cali, Colombia, Tel +57 301 4158934, Email [email protected]: Central venous oxygen saturation (ScvO2) has been reported as a prognostic marker of in-hospital mortality when it is below 60% in certain situations. Nevertheless, it has not been widely reported in patients undergoing coronary artery bypass graft (CABG). The study determined the association between ScvO2 and in-hospital mortality in patients undergoing CABG in a high-complexity health institution in Santiago de Cali, Colombia.Patients and Methods: A retrospective cohort study was conducted with patients undergoing isolated CABG. The subject sample included 515 subjects aged 18 years or older. Exposure was defined as ScvO2 75 years), low socioeconomic stratum, chronic kidney failure before surgery, unstable angina before surgery, ischemia time (> 60 min), and intra-operative inotrope use. The primary cause of death was cardiogenic shock (54.7%), followed by sepsis (25.0%) and postoperative bleeding (17.2%).Conclusion: The study identified an association between ScvO2 < 60% and in-hospital mortality in patients undergoing CABG.Keywords: coronary artery bypass, postoperative complications, mortality, critical care, risk factor
