601 An imbalance between regulatory and pro-inflammatory T cell subsets distinguishes symptomatic from asymptomatic individuals with anti-nuclear antibodies

• Sindhu R Johnson,
• Zahi Touma,
• Linda T Hiraki,
• Arthur Bookman,
• Kieran Manion,
• Dennisse Bonilla,
• Michael Kim,
• Emma Vanlieshout,
• Rashi Gupta,
• Zareen Ahmad,
• Joan E Wither

Affiliations

Sindhu R Johnson

Division of Rheumatology, Department of Medicine, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada

Zahi Touma

Division of Rheumatology, Department of Medicine, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada

Linda T Hiraki

1Division of Rheumatology, Immunology & Allergy, Brigham & Women`s Hospital and Harvard Medical School, Boston, Massachusetts, USA

Arthur Bookman

3Division of Rheumatology, University Health Network, Toronto, Canada

Kieran Manion

1Krembil Research Institute, University Health Network, Toronto, Canada

Dennisse Bonilla

1Krembil Research Institute, University Health Network, Toronto, Canada

Michael Kim

Division of Adolescent Medicine, Cincinnati Children`s Hospital Medical Center, Cincinnati, Ohio, USA

Emma Vanlieshout

1Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Canada

Rashi Gupta

1Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Canada

Zareen Ahmad

2Toronto Scleroderma Program, Division of Rheumatology, Toronto Western and Mount Sinai Hospitals, Toronto, Canada

Joan E Wither

1Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Canada