Phytochemical investigation and antimicrobial activity of Derris scandens

Hidayat Hussain; Ahmed Al-Harrasi; Karsten Krohn; Simeon F. Kouam; Ghulam Abbas; Afzal Shah; Muhammad Adil Raees; Riaz Ullah; Shahid Aziz; Barbara Schulz

doi:10.1016/j.jksus.2015.01.001

Journal of King Saud University: Science (Oct 2015)

Phytochemical investigation and antimicrobial activity of Derris scandens

Hidayat Hussain,
Ahmed Al-Harrasi,
Karsten Krohn,
Simeon F. Kouam,
Ghulam Abbas,
Afzal Shah,
Muhammad Adil Raees,
Riaz Ullah,
Shahid Aziz,
Barbara Schulz

Affiliations

Hidayat Hussain: Department of Chemistry, University of Paderborn, Warburger Strasse 100, 33098 Paderborn, Germany
Ahmed Al-Harrasi: UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, P.O. Box 33, Postal Code 616, Birkat Al Mauz, Nizwa, Oman
Karsten Krohn: Department of Chemistry, University of Paderborn, Warburger Strasse 100, 33098 Paderborn, Germany
Simeon F. Kouam: Department of Chemistry, Higher Teachers’ Training College, University of Yaounde 1, BP 47 Yaounde, Cameroon
Ghulam Abbas: UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, P.O. Box 33, Postal Code 616, Birkat Al Mauz, Nizwa, Oman
Afzal Shah: Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan
Muhammad Adil Raees: UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, P.O. Box 33, Postal Code 616, Birkat Al Mauz, Nizwa, Oman
Riaz Ullah: Department of Chemistry, Government College Ara Khel, FR Kohat, Khyber Pakhtunkhwa 26000, Pakistan
Shahid Aziz: Department of Chemistry, Mirpur University of Science and Technology, Mirpur, AJK, Pakistan
Barbara Schulz: Institute of Microbiology, University of Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany

DOI: https://doi.org/10.1016/j.jksus.2015.01.001
Journal volume & issue: Vol. 27, no. 4
pp. 375 – 378

Abstract

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Different fractions of root and stem of Derris scandens demonstrated good antibacterial (Escherichia coli, and Bacillus megaterium), antialgal (Chlorella fusca), and antifungal (Microbotryum violaceum) activities. Phytochemical investigation resulted in isolation of scandenin, scandenin A, betulinic acid, lupeol, β-amyran-3-one, β-amyrin, β-sitosterol and ß-sitosterol glucopyranoside. Study showed that scandenin has strong antibacterial activity against B. megaterium and good antifungal and antialgal properties. Scandenin A showed good antibacterial, antifungal and antialgal properties.

Published in Journal of King Saud University: Science

ISSN: 1018-3647 (Print)
Publisher: Elsevier
Country of publisher: Saudi Arabia
LCC subjects: Science: Science (General)
Website: http://www.journals.elsevier.com/journal-of-king-saud-university-science/

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