Nature Communications (Aug 2016)
Extension of human lncRNA transcripts by RACE coupled with long-read high-throughput sequencing (RACE-Seq)
- Julien Lagarde,
- Barbara Uszczynska-Ratajczak,
- Javier Santoyo-Lopez,
- Jose Manuel Gonzalez,
- Electra Tapanari,
- Jonathan M. Mudge,
- Charles A. Steward,
- Laurens Wilming,
- Andrea Tanzer,
- Cédric Howald,
- Jacqueline Chrast,
- Alicia Vela-Boza,
- Antonio Rueda,
- Francisco J. Lopez-Domingo,
- Joaquin Dopazo,
- Alexandre Reymond,
- Roderic Guigó,
- Jennifer Harrow
Affiliations
- Julien Lagarde
- Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST)
- Barbara Uszczynska-Ratajczak
- Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST)
- Javier Santoyo-Lopez
- Genomics and Bioinformatics Platform of Andalusia (GBPA)
- Jose Manuel Gonzalez
- Wellcome Trust Sanger Institute, Hinxton
- Electra Tapanari
- Wellcome Trust Sanger Institute, Hinxton
- Jonathan M. Mudge
- Wellcome Trust Sanger Institute, Hinxton
- Charles A. Steward
- Wellcome Trust Sanger Institute, Hinxton
- Laurens Wilming
- Wellcome Trust Sanger Institute, Hinxton
- Andrea Tanzer
- Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST)
- Cédric Howald
- Center for Integrative Genomics, University of Lausanne
- Jacqueline Chrast
- Center for Integrative Genomics, University of Lausanne
- Alicia Vela-Boza
- Genomics and Bioinformatics Platform of Andalusia (GBPA)
- Antonio Rueda
- Genomics and Bioinformatics Platform of Andalusia (GBPA)
- Francisco J. Lopez-Domingo
- Genomics and Bioinformatics Platform of Andalusia (GBPA)
- Joaquin Dopazo
- Genomics and Bioinformatics Platform of Andalusia (GBPA)
- Alexandre Reymond
- Center for Integrative Genomics, University of Lausanne
- Roderic Guigó
- Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST)
- Jennifer Harrow
- Wellcome Trust Sanger Institute, Hinxton
- DOI
- https://doi.org/10.1038/ncomms12339
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 11
Abstract
Long non-coding RNAs are increasingly recognised to be important factors in regulating cellular processes and comprise a large faction of the transcriptome, however most are uncharacterised. Here the authors present RACE-Seq, a tool to improve and extend the annotation of low-expression transcripts.
