Diagnostics (Dec 2023)

Review on Pediatric Malignant Focal Liver Lesions with Imaging Evaluation: Part II

  • Yi Dong,
  • Andrius Cekuolis,
  • Dagmar Schreiber-Dietrich,
  • Rasa Augustiniene,
  • Simone Schwarz,
  • Kathleen Möller,
  • Nasenien Nourkami-Tutdibi,
  • Sheng Chen,
  • Jia-Ying Cao,
  • Yun-Lin Huang,
  • Ying Wang,
  • Heike Taut,
  • Lara Grevelding,
  • Christoph F. Dietrich

DOI
https://doi.org/10.3390/diagnostics13243659
Journal volume & issue
Vol. 13, no. 24
p. 3659

Abstract

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Malignant focal liver lesions (FLLs) represent various kinds of epithelial and mesenchymal tumors. In pediatric patients, the understanding of pediatric liver diseases and associated imaging manifestations is essential for making accurate diagnosis and differential diagnosis. This paper will discuss the latest knowledge of the common pediatric malignant FLLs, including undifferentiated embryonal sarcoma, rhabdomyosarcoma, epithelioid hemangioendothelioma, angiosarcoma, and malignant rhabdoid tumor. Medical imaging features are not only helpful for clinical diagnosis, but can also be useful in the evaluation and follow-up of pre- and post-treatment. The future perspectives of contrast-enhanced ultrasound (CEUS) enhancement patterns of FLLs in pediatric patients are also mentioned.

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