Open Chemistry (Jan 2021)

GC-MS analysis of mango stem bark extracts (Mangifera indica L.), Haden variety. Possible contribution of volatile compounds to its health effects

  • Núñez Sellés Alberto J.,
  • Agüero Juan Agüero,
  • Paz Lauro Nuevas

DOI
https://doi.org/10.1515/chem-2021-0192
Journal volume & issue
Vol. 19, no. 1
pp. 27 – 38

Abstract

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Mango stem bark extracts (MSBE) have been used as bioactive ingredients for nutraceutical, cosmeceutical, and pharmaceutical formulations due to their antioxidant, anti-inflammatory, and analgesic effects. We performed the MSBE preparative column liquid chromatography, which led to the resolution and identification by GC-MS of 64 volatile compounds: 7 hydrocarbons, 3 alcohols, 1 ether, 3 aldehydes/ketones, 7 phenols, 20 terpenoids (hydrocarbons and oxygenated derivatives), 9 steroids, 4 nitrogen compounds, and 1 sulphur compound. Major components were β-elemene, α-guaiene, aromadendrene, hinesol, 1-octadecene, β-eudesmol, methyl linoleate, juniper camphor, hinesol, 9-methyl (3β,5α)-androstan-3-ol, γ-sitosterol, β-chamigrene, 2,5-dihydroxymethyl-phenetylalcohol, N-phenyl-2-naphtaleneamine, and several phenolic compounds. The analysis of MSBE, Haden variety, by GC-MS is reported for the first time, which gives an approach to understand the possible synergistic effect of volatile compounds on its antioxidant, analgesic, and anti-inflammatory effects. The identification of relevant bioactive volatile components from MSBE extracts, mainly terpenes from the eudesmane family, will contribute to correlate its chemical composition to previous determined pharmacological effects.

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