SIBO in pediatric population: literature review on pathogenesis, symptoms, diagnosis and treatment

Abstract

Introduction: SIBO is a condition characterized by bacterial overgrowth in the small intestine which is caused by various factors. The excessively proliferated bacteria can lead to digestive disturbances- manifesting as gastrointestinal symptoms and malabsorption. In pediatric patients, small intestinal bacterial overgrowth can also result in growth retardation. Due to many challenges related to the diagnosis and treatment of children- this condition should be well known by pediatric healthcare providers. Aim of the study: This study aims to summarizes the recent knowledge about the pathogenesis, symptoms, diagnosis and the treatment of small intestine bacterial overgrowth in pediatric population, providing an overview for healthcare professionals. Material and methods: The literature available in the PubMed database was reviewed using the following keywords: „SIBO”, „Small Intestinal Bacterial Overgrowth”, ,, „SIBO in pediatric population”, „Endoscopy in children”, „SIBO treatment” Conclusion: Small intestinal bacterial overgrowth is a complex disorder that can have a significant influence on the quality of life of pediatric patients. The variety of symptoms of this syndrome can lead to confusing clinical findings. The diagnostic pathway consists of a clinical evaluation and specific tests, to verify the presence of bacterial overgrowth. Effective treatment involves modifying the intestinal microbiota - mostly through antibiotic therapy - and supplementing nutritional deficiencies. Probiotics and dietary modifications, such as low-FODMAP diets, are often used as adjunctive therapies.

Keywords

• „SIBO
• Small Intestinal Bacterial Overgrowth
• SIBO in pediatric population
• gastrointestinal symptoms
• „SIBO diagnosis