Global Medical Genetics (Sep 2023)

BL-MOL-AR Project, Preliminary Results about Liquid Biopsy: Molecular Approach Experience and Research Activity in Oncological Settings

  • Pancrazzi Pancrazzi,
  • Bloise Bloise,
  • Moncada Moncada,
  • Perticucci Perticucci,
  • Vecchietti Vecchietti,
  • Pompili Pompili,
  • Ricciarini Ricciarini,
  • Lenzi Lenzi,
  • Gatteschi Gatteschi,
  • Giusti Giusti,
  • Rosito Rosito,
  • Del Buono Del Buono,
  • Belardi Belardi,
  • Bruni Bruni,
  • Borri Borri,
  • Campione Campione,
  • Laurini Laurini,
  • Occhini Occhini,
  • Presenti Presenti,
  • Viticchi Viticchi,
  • Rossi Rossi,
  • Bardi Bardi,
  • D'Urso D'Urso,
  • Dei Dei,
  • Venezia Venezia,
  • Scala Scala,
  • Bengala Bengala,
  • Decarli Decarli,
  • Carnevali Carnevali,
  • Milandri Milandri,
  • Ognibene Ognibene

DOI
https://doi.org/10.1055/s-0043-1771193
Journal volume & issue
Vol. 10, no. 03
pp. 172 – 187

Abstract

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Background Liquid biopsy is mainly used to identify tumor cells in pulmonary neoplasms. It is more often used in research than in clinical practice. The BL-MOL-AR study aims to investigate the efficacy of next-generation sequencing (NGS) and clinical interpretation of the circulating free DNA (cfDNA) levels. This study reports the preliminary results from the first samples analyzed from patients affected by various neoplasms: lung, intestinal, mammary, gastric, biliary, and cutaneous.

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