Nature Communications (Mar 2018)

Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase

  • Fangfang Li,
  • Changwei Zhang,
  • Yinzi Li,
  • Guanwei Wu,
  • Xilin Hou,
  • Xueping Zhou,
  • Aiming Wang

DOI
https://doi.org/10.1038/s41467-018-03658-2
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 17

Abstract

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Plant DNA virus replication is inhibited by autophagy, but the interplay between plant RNA viruses and autophagy is less clear. Here, Li et al. show that turnip mosaic virus infection activates autophagy and that Beclin1, a core autophagy component, binds the viral polymerase and inhibits virus replication.