Green Processing and Synthesis (Apr 2013)
A facile synthesis of 2H-chromen-2-ones via Pechmann condensation under solvent free conditions using grinding technique
Abstract
A simple and highly efficient procedure for the synthesis of 2H-chromen-2-ones via von Pechmann condensation, involving the grinding of different phenols and β-ketoesters in the presence of silica supported sulfuric acid at room temperature, under solvent free conditions, has been described.
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