Development and external validation of a radiomics model for assessment of HER2 positivity in men and women presenting with gastric cancer

Huiping Zhao; Pan Liang; Liuliang Yong; Ming Cheng; Yan Zhang; Minggang Huang; Jianbo Gao

doi:10.1186/s13244-022-01361-x

Insights into Imaging (Feb 2023)

Development and external validation of a radiomics model for assessment of HER2 positivity in men and women presenting with gastric cancer

Huiping Zhao,
Pan Liang,
Liuliang Yong,
Ming Cheng,
Yan Zhang,
Minggang Huang,
Jianbo Gao

Affiliations

Huiping Zhao: Department of CT, Shaanxi Provincial People’s Hospital
Pan Liang: Department of Radiology, The First Affiliated Hospital of Zhengzhou University
Liuliang Yong: Department of Radiology, The First Affiliated Hospital of Zhengzhou University
Ming Cheng: Henan Key Laboratory of Image Diagnosis and Treatment for Digestive System Tumor & Henan International Joint Laboratory of Medical Imaging & Henan Engineering Laboratory of Tumor Imaging & Henan Key Laboratory of CT Imaging & Zhengzhou Key Laboratory of Medical Imaging Technology and Diagnosis
Yan Zhang: Department of CT, Shaanxi Provincial People’s Hospital
Minggang Huang: Department of CT, Shaanxi Provincial People’s Hospital
Jianbo Gao: Department of Radiology, The First Affiliated Hospital of Zhengzhou University

DOI: https://doi.org/10.1186/s13244-022-01361-x
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 13

Abstract

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Key points Radiomics model holds promise in identifying HER2 positivity in GCs. The conventional CT-based HER2-specific radiomics model might generalize to DECT. This study provides an imaging surrogate for stratifying GC by HER2 expression.

Published in Insights into Imaging

ISSN: 1869-4101 (Online)
Publisher: SpringerOpen
Country of publisher: Germany
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: http://www.springer.com/13244

About the journal

Abstract

Keywords