Nature Communications (Feb 2021)

Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features

  • Natalya Yutin,
  • Sean Benler,
  • Sergei A. Shmakov,
  • Yuri I. Wolf,
  • Igor Tolstoy,
  • Mike Rayko,
  • Dmitry Antipov,
  • Pavel A. Pevzner,
  • Eugene V. Koonin

DOI
https://doi.org/10.1038/s41467-021-21350-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

Read online

Here, the authors analyze 4907 Circular Metagenome Assembled Genomes from human microbiomes and identify and characterize nearly 600 diverse genomes of crAss-like phages, finding two putative families with unusual genomic features, including high density of self-splicing introns and inteins.