PLoS Neglected Tropical Diseases (Nov 2017)

Scabies in the age of increasing drug resistance.

  • Samar Khalil,
  • Ossama Abbas,
  • Abdul Ghani Kibbi,
  • Mazen Kurban

DOI
https://doi.org/10.1371/journal.pntd.0005920
Journal volume & issue
Vol. 11, no. 11
p. e0005920

Abstract

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Scabies is an infestation of the skin by the mite Sarcoptes scabiei. It manifests with pruritic erythematous papules and excoriations, in addition to the pathognomonic burrows. Multiple drugs can be used for treatment, but resistance to conventional therapy is increasing throughout the years. This paper will review the mechanisms of resistance proposed in the literature and some of the potential solutions to this problem.