Ca2+-regulated Ca2+ channels with an RCK gating ring control plant symbiotic associations

Sunghoon Kim; Weizhong Zeng; Shane Bernard; Jun Liao; Muthusubramanian Venkateshwaran; Jean-Michel Ane; Youxing Jiang

doi:10.1038/s41467-019-11698-5

Nature Communications (Aug 2019)

Ca2+-regulated Ca2+ channels with an RCK gating ring control plant symbiotic associations

Sunghoon Kim,
Weizhong Zeng,
Shane Bernard,
Jun Liao,
Muthusubramanian Venkateshwaran,
Jean-Michel Ane,
Youxing Jiang

Affiliations

Sunghoon Kim: Howard Hughes Medical Institute and Department of Physiology, University of Texas Southwestern Medical Center
Weizhong Zeng: Howard Hughes Medical Institute and Department of Physiology, University of Texas Southwestern Medical Center
Shane Bernard: Department of Bacteriology, University of Wisconsin-Madison
Jun Liao: School of Life Science and Technology, ShanghaiTech University
Muthusubramanian Venkateshwaran: School of Agriculture, University of Wisconsin-Platteville
Jean-Michel Ane: Department of Bacteriology, University of Wisconsin-Madison
Youxing Jiang: Howard Hughes Medical Institute and Department of Physiology, University of Texas Southwestern Medical Center

DOI: https://doi.org/10.1038/s41467-019-11698-5
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 12

Abstract

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CASTOR is a Lotus japonicus ion channel required for nuclear Ca2+ spiking and establishing rhizobial and mycorrhizal symbioses. Here, via structural and functional analysis, Kim et al. show that CASTOR is a Ca2+-selective channel activated via Ca2+ binding to a soluble gating ring consisting of tandem RCK domains.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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