Spatio-temporal distribution characteristics of the risk of viral hepatitis B incidence based on INLA in 14 prefectures of Xinjiang from 2004 to 2019

Abstract

This study aimed to explore the spatio-temporal distribution characteristics and risk factors of hepatitis B (HB) in 14 prefectures of Xinjiang, China, and to provide a relevant reference basis for the prevention and treatment of HB. Based on HB incidence data and risk factor indicators in 14 prefectures in Xinjiang from 2004 to 2019, we explored the distribution characteristics of the risk of HB incidence using global trend analysis and spatial autocorrelation analysis and established a Bayesian spatiotemporal model to identify the risk factors of HB and their spatio-temporal distribution to fit and extrapolate the Bayesian spatiotemporal model using the Integrated Nested Laplace Approximation (INLA) method. There was spatial autocorrelation in the risk of HB and an overall increasing trend from west to east and north to south. The natural growth rate, per capita GDP, number of students, and number of hospital beds per 10, 000 people were all significantly associated with the risk of HB incidence. From 2004 to 2019, the risk of HB increased annually in 14 prefectures in Xinjiang, with Changji Hui Autonomous Prefecture, Urumqi City, Karamay City, and Bayangol Mongol Autonomous Prefecture having the highest rates.

Keywords

• hepatitis b
• bayesian spatiotemporal model
• inla method
• risk factor