Chloroquine Cardiotoxicity Leading to Cardiogenic Shock

Madeleine Alder, MD; Richa Gupta, MD, MPH; Giovanni E. Davogustto, MD; Meghan E. Kapp, MD, MS; JoAnn Lindenfeld, MD

JACC: Case Reports (Dec 2020)

Chloroquine Cardiotoxicity Leading to Cardiogenic Shock

Madeleine Alder, MD,
Richa Gupta, MD, MPH,
Giovanni E. Davogustto, MD,
Meghan E. Kapp, MD, MS,
JoAnn Lindenfeld, MD

Affiliations

Madeleine Alder, MD: Divison of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Richa Gupta, MD, MPH: Division of Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Address for correspondence: Dr. Richa Gupta, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, 1215 21st Avenue South, Suite 5209, Nashville, Tennessee 37232, USA.
Giovanni E. Davogustto, MD: Division of Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Meghan E. Kapp, MD, MS: Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
JoAnn Lindenfeld, MD: Division of Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

Journal volume & issue: Vol. 2, no. 15
pp. 2381 – 2386

Abstract

Read online

A patient with a history of heart block and longstanding chloroquine use presented in cardiogenic shock refractory to medical therapy and mechanical circulatory support. Autopsy supported antimalarial-induced cardiomyopathy (AMIC). Progression of AMIC may be halted with early recognition and cessation of antimalarial therapy, highlighting importance of screening and timely diagnosis. (Level of Difficulty: Beginner.)

Published in JACC: Case Reports

ISSN: 2666-0849 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.journals.elsevier.com/jacc-case-reports

About the journal

Abstract

Keywords