Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light

Shiqian Zhang; Quansheng Mou; Bowen Cao; Tongyu Han; Mingxin Liu

Tetrahedron Green Chem (Dec 2024)

Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light

Shiqian Zhang,
Quansheng Mou,
Bowen Cao,
Tongyu Han,
Mingxin Liu

Affiliations

Shiqian Zhang: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, China
Quansheng Mou: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, China
Bowen Cao: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, China
Tongyu Han: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, China
Mingxin Liu: Corresponding author.; State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, China

Journal volume & issue: Vol. 4
p. 100056

Abstract

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Carbonyl compounds are widely found in various chemical reactions and natural products. Herein, a light-driven carbonylative cross-coupling reaction of bromobenzene was reported. Co2(CO)8 was used as an abundant solid carbonyl source to synthesize various Michael addition products with high yields. This reaction has broad substrates scope with good functional group tolerance. The mechanism study indicated that the reaction is achieved by the formation of benzoyl radical from homolytic C–Co cleavage under irradiation.

Published in Tetrahedron Green Chem

ISSN: 2773-2231 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Science: Chemistry
Website: https://www.sciencedirect.com/journal/tetrahedron-green-chem

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Abstract

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