Deep learning facilitates efficient optimization of antisense oligonucleotide drugs

• Shenggeng Lin,
• Liang Hong,
• Dong-Qing Wei,
• Yi Xiong

Affiliations

Shenggeng Lin

State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China; Artificial Intelligence Biomedical Center, Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai, China

Liang Hong

Artificial Intelligence Biomedical Center, Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai, China; Shanghai Artificial Intelligence Laboratory, Shanghai, China; Institute of Natural Sciences, Shanghai Jiao Tong University, Shanghai, China

Dong-Qing Wei

State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

Yi Xiong

State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China; Artificial Intelligence Biomedical Center, Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai, China; Shanghai Artificial Intelligence Laboratory, Shanghai, China; Corresponding author: Yi Xiong, State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.