Nature Communications (Jul 2021)

Oil immersed lossless total analysis system for integrated RNA extraction and detection of SARS-CoV-2

  • Duane S. Juang,
  • Terry D. Juang,
  • Dawn M. Dudley,
  • Christina M. Newman,
  • Molly A. Accola,
  • William M. Rehrauer,
  • Thomas C. Friedrich,
  • David H. O’Connor,
  • David J. Beebe

DOI
https://doi.org/10.1038/s41467-021-24463-4
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Bottlenecks in qPCR-based COVID-19 diagnostics include the lengthy multistep process and reagent shortages. Here the authors report OIL-TAS which integrates RNA extraction and detection into a single device.