Retrospective examination of endometrial sampling results in women with abnormal uterine bleeding

Abstract

Background: Abnormal uterine bleeding (AUB) is among the most significant and frequent causes of admission to the gynecology outpatient clinic. AUBs may manifest as the earliest sign of endometrial cancer. For the early detection and treatment of endometrial cancer, careful examination of AUBs is crucial. Aim: The study was conducted to retrospectively evaluate the histopathological results of probe curettage materials applied to women who applied to the gynecology clinic for AUB and were hospitalized with the complaint of AUB. Material and Methods: In the retrospective study planned between 2020 and 2021, all endometrial biopsies from 638 women with AUB reported to the gynecology clinic were reviewed and analyzed. The data were obtained from the archives of our hospital's gynecology and obstetrics clinic and pathology clinic. Results: 638 cases were analyzed. The mean age of the patients was 47.94±9.53 years. Malignant pathology was detected in 20 cases (3.13%). Nineteen of these cases were seen in postmenopausal women. The most common pathology was found to be benign polyps at a rate of 19.91%. It was the most common benign pathology in women pre- and postmenopausal. Adenocarcinoma was detected in 13 (2.03%) postmenopausal cases while in only 1 (0.16%) of the premenopausal women. Conclusion: Since more malignant pathologies are observed in postmenopausal women, women with asymptomatic or AUB complaints should be carefully monitored, and endometrial evaluation should not be skipped. Endometrial biopsies are valuable in the early detection of pre-cancerous and cancerous endometrial lesions, especially in postmenopausal women.

Keywords

• endometrial cancer
• abnormal uterine bleeding
• endometrial carcinoma