Tomography (Oct 2024)

Diagnostic Value of Contrast-Enhanced Dual-Energy Computed Tomography in the Pancreatic Parenchymal and Delayed Phases for Pancreatic Cancer

  • Yusuke Kurita,
  • Daisuke Utsunomiya,
  • Kensuke Kubota,
  • Shingo Koyama,
  • Sho Hasegawa,
  • Kunihiro Hosono,
  • Kuniyasu Irie,
  • Yuichi Suzuki,
  • Shin Maeda,
  • Noritoshi Kobayashi,
  • Yasushi Ichikawa,
  • Itaru Endo,
  • Atsushi Nakajima

DOI
https://doi.org/10.3390/tomography10100117
Journal volume & issue
Vol. 10, no. 10
pp. 1591 – 1604

Abstract

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Background/Objectives: The usefulness of dual-energy computed tomography (DECT) for low absorption in the parenchymal phase and contrast effects in the delayed phase for pancreatic cancer is not clear. Therefore, the diagnostic capability of low-KeV images obtained using DECT for pancreatic cancer in the pancreatic parenchymal and delayed phases was evaluated quantitatively and qualitatively. Methods: Twenty-five patients with pancreatic cancer who underwent contrast-enhanced DECT were included. A total of 50 and 70 KeV CT images, classified as low-keV and conventional CT-equivalent images, were produced, respectively. The tumor-to-pancreas contrast (Hounsfield units [HU]) in the pancreatic parenchymal and delayed phases was calculated by subtracting the CT value of the pancreatic tumor from that of normal parenchyma. Results: The median tumor-to-pancreas contrast on 50 KeV CT in the pancreatic parenchymal phase (133 HU) was higher than that on conventional CT (68 HU) (p p = 0.545). For tumors p = 0.034). Conclusions: These 50 KeV CT images may clarify the low-absorption areas of pancreatic cancer in the pancreatic parenchymal phase. A good contrast effect was observed in small pancreatic cancers on 50 KeV delayed-phase images, suggesting that DECT is useful for the visualization of early pancreatic cancer with a small tumor diameter.

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