Nursing Open (Sep 2021)

Effect of open versus closed endotracheal suctioning on intracranial pressure in severe brain‐injured children: Study protocol for a randomized controlled trial

  • Yan Li,
  • Xiaoyan Li,
  • Zunjia Wen,
  • Xin Zhang,
  • Yingfei Liu,
  • Li Wei

DOI
https://doi.org/10.1002/nop2.656
Journal volume & issue
Vol. 8, no. 5
pp. 2886 – 2891

Abstract

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Abstract Aim To compare the effects and safety of open and closed endotracheal suction in children with severe brain injury. Design A single‐blinding, single‐centre randomized controlled trial (RCT). Methods The children with severe brain injury admitted to the intensive care unit (ICU) from 1 September 2020–31 August 2022 will be included. And a total of 172 children with severe brain injury are expected to be included. The intracranial pressure, SpO2 and heart rate before suctioning, at the end of suction, and at 5 and 10 min after suction, the estimated sputum volume for each suction, the incidence of ventilator‐associated pneumonia, the duration of mechanical ventilation and the length of ICU stay will be analysed. Results This present RCT has been prospectively registered in China Clinical Trial Registry (http://www.chictr.org.cn, ChiCTR2000030963). This present study is expected to provide reliable evidence to the airway management in children with severe brain injury.

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