An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits

Dominique Förster; Marco Dal Maschio; Eva Laurell; Herwig Baier

doi:10.1038/s41467-017-00160-z

Nature Communications (Jul 2017)

An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits

Dominique Förster,
Marco Dal Maschio,
Eva Laurell,
Herwig Baier

Affiliations

Dominique Förster: Department Genes—Circuits—Behavior, Max Planck Institute of Neurobiology
Marco Dal Maschio: Department Genes—Circuits—Behavior, Max Planck Institute of Neurobiology
Eva Laurell: Department Genes—Circuits—Behavior, Max Planck Institute of Neurobiology
Herwig Baier: Department Genes—Circuits—Behavior, Max Planck Institute of Neurobiology

DOI: https://doi.org/10.1038/s41467-017-00160-z
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 12

Abstract

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Mechanisms of neural processing can only be understood by revealing patterns of connectivity among the cellular components of the circuit. Here the authors report a new genetic toolbox, ‘Optobow’, which enables simultaneous optogenetic activation of single neurons in zebrafish and measuring the activity of downstream neurons in the network.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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