The loss of Profilin 1 is associated with early-onset Paget's disease of bone degenerating into osteosarcoma

• Federica Scotto di Carlo,
• Sharon Russo,
• Laura Pazzaglia,
• Teresa Esposito,
• Carmine Settembre,
• Fernando Gianfrancesco

Affiliations

Federica Scotto di Carlo

Institute of Genetics and Biophysics, Italian National Research Council, Naples, Italy; Corresponding author.

Sharon Russo

Institute of Genetics and Biophysics, Italian National Research Council, Naples, Italy

Laura Pazzaglia

Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

Teresa Esposito

Institute of Genetics and Biophysics, Italian National Research Council, Naples, Italy; IRCCS INM Neuromed, Pozzilli, Italy

Carmine Settembre

Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy

Fernando Gianfrancesco

Institute of Genetics and Biophysics, Italian National Research Council, Naples, Italy