Nature Communications (Aug 2017)

In vivo cation exchange in quantum dots for tumor-specific imaging

  • Xiangyou Liu,
  • Gary B. Braun,
  • Mingde Qin,
  • Erkki Ruoslahti,
  • Kazuki N. Sugahara

DOI
https://doi.org/10.1038/s41467-017-00153-y
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 13

Abstract

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The imaging of tumors in vivo using nanoprobes has been challenging due to the lack of sufficient tumor specificity. Here, the authors develop a tumor-specific quantum dot system that permits in vivo cation exchange to achieve selective background quenching and high tumor-specific imaging.