Disease Models & Mechanisms (Oct 2019)

Drosophila melanogaster: a simple system for understanding complexity

  • Stephanie E. Mohr,
  • Norbert Perrimon

DOI
https://doi.org/10.1242/dmm.041871
Journal volume & issue
Vol. 12, no. 10

Abstract

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Understanding human gene function is fundamental to understanding and treating diseases. Research using the model organism Drosophila melanogaster benefits from a wealth of molecular genetic resources and information useful for efficient in vivo experimentation. Moreover, Drosophila offers a balance as a relatively simple organism that nonetheless exhibits complex multicellular activities. Recent examples demonstrate the power and continued promise of Drosophila research to further our understanding of conserved gene functions.