Recent advances in small incision lenticule extraction (SMILE)-derived refractive lenticule preservation and clinical reuse

Xiaojun Hu; Ruoyan Wei; Chang Liu; Yunzhe Wang; Danjuan Yang; Ling Sun; Fei Xia; Shengtao Liu; Meiyan Li; Xingtao Zhou

Engineered Regeneration (Jun 2023)

Recent advances in small incision lenticule extraction (SMILE)-derived refractive lenticule preservation and clinical reuse

Xiaojun Hu,
Ruoyan Wei,
Chang Liu,
Yunzhe Wang,
Danjuan Yang,
Ling Sun,
Fei Xia,
Shengtao Liu,
Meiyan Li,
Xingtao Zhou

Affiliations

Xiaojun Hu: Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University); Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, China
Ruoyan Wei: Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University); Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, China
Chang Liu: Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University); Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, China
Yunzhe Wang: Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University); Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, China
Danjuan Yang: Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University); Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, China
Ling Sun: Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University); Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, China
Fei Xia: Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University); Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, China
Shengtao Liu: Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University); Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, China
Meiyan Li: Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University); Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, China; Corresponding authors at: Department of Ophthalmology, Key Lab of Myopia, Ministry of Health, Eye and ENT Hospital of Fudan University, Shanghai, China.
Xingtao Zhou: Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University); Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, China; Corresponding authors at: Department of Ophthalmology, Key Lab of Myopia, Ministry of Health, Eye and ENT Hospital of Fudan University, Shanghai, China.

Journal volume & issue: Vol. 4, no. 2
pp. 103 – 121

Abstract

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Small incision lenticule extraction (SMILE) has become one of the mainstream refractive surgeries in recent years, with satisfactory efficacy, safety, and predictability. SMILE-derived refractive lenticule, the byproduct of the surgery, holds great potential in clinical practice given its easy access and good biocompatibility. Numerous studies have been published to describe its applications in refractive correction, corneal ectasia diseases, and corneal defects. The feasibility and safety were validated in both animal models and clinical studies. Moreover, the preservation method is also crucial for its further promotion and application. Novel techniques are also evaluated and applied in lenticule preservation. We covered the recent advances in the preservation of corneal stromal lenticules and their clinical reuse in this review.

Published in Engineered Regeneration

ISSN: 2666-1381 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Science: Biology (General): Life
Website: https://www.keaipublishing.com/en/journals/engineered-regeneration/

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