This data article is related to our recently published research paper “Exploiting a new glycerol-based copolymer as a route to wound healing: synthesis, characterization and biocompatibility assessment'', De Giglio et al. (Colloids and Surfaces B: Biointerfaces 136 (2015) 600–611) [1]. The latter described a new copolymer derived from glycerol and tartaric acid (PGT). Herein, an investigation about the PGT-ciprofloxacin (CIP) interactions by means of Fourier Transform Infrared Spectroscopy (FT-IR) acquired in Attenuated Total Reflectance (ATR) mode and Differential Scanning Calorimetry (DSC) was reported. Moreover, CIP release experiments on CIP-PGT patches were performed by High Performance Liquid Chromatography (HPLC) at different pH values. Keywords: Glycerol-based copolymer, Differential Scanning Calorimetry (DSC), Fourier Transform Infrared Spectroscopy (FT-IR), Drug release
