Diagnosi di infezione acuta primaria da HIV in donatore di sangue

Abstract

The early detection of HIV infection is of paramount either to achieve a better blood supply safety and to pose a prompt diagnosis so that to decrease the involuntary spreading of the disease.The fourth generation screening assays, which measure both the levels of the anti-HIV antibodies and the p-24 viral antigen, and mainly the development and widespread usage of the molecular biology tests, which identify the HIV-RNA in the early stage, have further reduced the diagnostic window period.We report a case about an acute primary HIV infection, occurred in a periodic donor, promptly diagnosed by the combined screening assays and the detection of HIV-RNA using molecular tests.

Keywords

• test screening HIV, primary infection, p24