Tropical Medicine and Infectious Disease (Oct 2022)

Clinical Features Related to Severity and Mortality among COVID-19 Patients in a Pre-Vaccine Period in Luanda, Angola

  • Cruz S. Sebastião,
  • Adis Cogle,
  • Alice D’Alva Teixeira,
  • Ana Micolo Cândido,
  • Chissengo Tchoni,
  • Maria João Amorim,
  • N’gueza Loureiro,
  • Paolo Parimbelli,
  • Carlos Penha-Gonçalves,
  • Jocelyne Demengeot,
  • Euclides Sacomboio,
  • Manuela Mendes,
  • Margarete Arrais,
  • Joana Morais,
  • Jocelyne Neto de Vasconcelos,
  • Miguel Brito

DOI
https://doi.org/10.3390/tropicalmed7110338
Journal volume & issue
Vol. 7, no. 11
p. 338

Abstract

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Background: Infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with clinical features of diverse severity. Few studies investigated the severity and mortality predictors of coronavirus disease 2019 (COVID-19) in Africa. Herein, we investigated the clinical features of severity and mortality among COVID-19 patients in Luanda, Angola. Methods: This multicenter cohort study involved 101 COVID-19 patients, between December 2020 and April 2021, with clinical and laboratory data collected. Analysis was done using independent-sample t-tests and Chi-square tests. The results were deemed significant when p p < 0.05). Conclusion: Several factors contributed to the severity and mortality among COVID-19 patients in Angola. Further studies related to clinical features should be carried out to help clinical decision-making and follow-up of COVID-19 patients in Angola.

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