Toxoplasmosis in rodents: A systematic review and meta-analysis in Iran

Shahram Khademvatan; Masoud Foroutan; Khosrow Hazrati-Tappeh; Sahar Dalvand; Hamidreza Khalkhali; Sajjad Masoumifard; Faezeh Hedayati-Rad

Journal of Infection and Public Health (Sep 2017)

Toxoplasmosis in rodents: A systematic review and meta-analysis in Iran

Shahram Khademvatan,
Masoud Foroutan,
Khosrow Hazrati-Tappeh,
Sahar Dalvand,
Hamidreza Khalkhali,
Sajjad Masoumifard,
Faezeh Hedayati-Rad

Affiliations

Shahram Khademvatan: Cellular and Molecular Research Center & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia, Iran
Masoud Foroutan: Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran; Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran; Corresponding author at: Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, & Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.
Khosrow Hazrati-Tappeh: Cellular and Molecular Research Center & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia, Iran
Sahar Dalvand: Social Determinants of Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran
Hamidreza Khalkhali: Inpatient’s Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran
Sajjad Masoumifard: Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran
Faezeh Hedayati-Rad: Department of Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran; Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran; Corresponding author at: Department of Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, & Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.

Journal volume & issue: Vol. 10, no. 5
pp. 487 – 493

Abstract

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During recent years, implication of rodents in the epidemiology of Toxoplasma gondii is overlooked in Iran; thus, we performed a systematic review and meta-analysis to evaluate the prevalence of toxoplasmosis in rodents of Iran. For this purpose, following the general methodology recommended for systematic reviews and meta-analysis, 5 English and 3 Persian databases were explored from 1 January 2000 till 10 September 2016 using related keywords. Finally, 9 out of 291 citations were met to be included in this study. Due to significant heterogeneity, the random-effects model was conducted (I2 = 93.55%). During the years, 661 rodents were trapped, and 121 of them were identified positive for T. gondii 15% (95% CI = 5–27). Moreover, overall prevalence using direct microscopic examination (1/230), PCR-based techniques (41/246) and serological tests (83/437) was obtained 0.1% (95% CI = 0.0–1.5), 18% (95% CI = 4–39) and 15% (95% CI = 3–33), respectively. Our study revealed the prevalence of toxoplasmosis in rodents is remarkable. Considering this fact, they play a key role in the life cycle of T. gondii and should not be neglected. Further surveys is needed to better recognize the role of various rodent species in distribution of toxoplasmosis. Keywords: Toxoplasma gondii, Rodents, Systematic review, Meta-analysis, Iran

Published in Journal of Infection and Public Health

ISSN: 1876-0341 (Print); 1876-035X (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Medicine: Public aspects of medicine
Website: https://www.journals.elsevier.com/journal-of-infection-and-public-health

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