Медицинская иммунология (Jul 2014)

MOLECULAR GENETIC ANALYSIS OF INTERLEUKIN 4 GENE POLYMORPHISM AMONG TELEUTIANS, SHORIANS, AND CAUCASIANS IN KEMEROVO REGION

  • A. V. Ostaptseva,
  • A. V. Shabaldin,
  • V. R. Akhmatianova,
  • V. I. Minina,
  • A. N. Glushkov,
  • V. G. Druzhinin,
  • I. V. Zorkoltseva,
  • E. V. Shabaldin,
  • O. A. Glushkova,
  • O. S. Makarchenko,
  • T. N. Ageeva

DOI
https://doi.org/10.15789/1563-0625-2006-5-6-737-740
Journal volume & issue
Vol. 8, no. 5-6
pp. 737 – 740

Abstract

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Abstract. An interleukin 4 polymorphism has been studied in Teleutians, Shorians, and Caucasoids living in the Kemerovo Region. The groups of Teleutians and Caucasoids are characterised with even or close-to-even distribution of the IL-4 alleles. The most widespread genotype in populations of Teleutians and Caucasoids was the 2R/3R heterozygosity, and 3R/3R proved to be the mostly rare. These data are indicative for mixing processes among Teleutians in the Kemerovo Region and Siberian Caucasoids. The major IL-4 genotype in Shorian population was 3R/3R, and the heterozygotic genotype 2R/3R took the second position.

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