PLoS ONE (Jan 2014)

Low birth weight is a risk factor for severe retinopathy of prematurity depending on gestational age.

  • Pia Lundgren,
  • Anna Kistner,
  • Eva M Andersson,
  • Ingrid Hansen Pupp,
  • Gerd Holmström,
  • David Ley,
  • Aimon Niklasson,
  • Lois E H Smith,
  • Carolyn Wu,
  • Ann Hellström,
  • Chatarina Löfqvist

DOI
https://doi.org/10.1371/journal.pone.0109460
Journal volume & issue
Vol. 9, no. 10
p. e109460

Abstract

Read online

ObjectiveTo evaluate the impact of low birth weight as a risk factor for retinopathy of prematurity (ROP) that will require treatment in correlation with gestational age at birth (GA).Study designIn total, 2941 infants born ResultsUnivariate analysis showed that low GA (pConclusionsLow BWSDS as a risk factor for vision-threatening ROP is dependent on the infant's degree of immaturity. In more mature infants (GA ≥26 weeks), low BWSDS becomes a major risk factor for developing ROP that will require treatment. These results persist even when calculating BW deficit with different well-established approaches.