“Another inchworm sign” on dynamic contrast-enhanced magnetic resonance imaging in pediatric patients with cystitis cystica and glandularis: Radiologic-pathologic correlation

Sota Masuoka, MD; Osamu Miyazaki, MD; Ayako Imai, MD; Reiko Okamoto, MD; Yoshiyuki Tsutsumi, MD; Mikiko Miyasaka, MD; Yuichi Hasegawa, MD; Takako Yoshioka, MD; Shunsuke Nosaka, MD

Radiology Case Reports (Mar 2023)

“Another inchworm sign” on dynamic contrast-enhanced magnetic resonance imaging in pediatric patients with cystitis cystica and glandularis: Radiologic-pathologic correlation

Sota Masuoka, MD,
Osamu Miyazaki, MD,
Ayako Imai, MD,
Reiko Okamoto, MD,
Yoshiyuki Tsutsumi, MD,
Mikiko Miyasaka, MD,
Yuichi Hasegawa, MD,
Takako Yoshioka, MD,
Shunsuke Nosaka, MD

Affiliations

Sota Masuoka, MD: Department of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan; Department of Diagnostic and Interventional Radiology, University of Tsukuba, Faculty of Medicine, 1-1-1, Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan
Osamu Miyazaki, MD: Department of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan; Corresponding author.
Ayako Imai, MD: Department of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan
Reiko Okamoto, MD: Department of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan
Yoshiyuki Tsutsumi, MD: Department of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan
Mikiko Miyasaka, MD: Department of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan
Yuichi Hasegawa, MD: Department of Urology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan
Takako Yoshioka, MD: Department of Pathology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan
Shunsuke Nosaka, MD: Department of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan

Journal volume & issue: Vol. 18, no. 3
pp. 840 – 843

Abstract

Read online

Cystitis cystica and glandularis is a hyperproliferative disease of the urothelium, and may form a papillary or polypoid mass. Clinically, these mass lesions are often difficult to distinguish from malignant tumors. We present a pediatric patient of cystitis cystica and glandularis with a bladder mass and discuss dynamic contrast-enhanced magnetic resonance imaging (MRI) findings and histopathological profiles, which have not been previously explored in the literature. Dynamic contrast-enhanced MRI showed unique, superficial, strong enhancement that resembles an inchworm in appearance. The term “inchworm sign” is a characteristic finding on diffusion-weighted MRI, proposed as a criterion for T-staging in non-muscle-invasive bladder cancer. We would like to propose another “inchworm sign” on dynamic contrast-enhanced MRI as a new hallmark of cystitis cystica and glandularis, which may differentiate it from a malignant tumor.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: http://www.journals.elsevier.com/radiology-case-reports/

About the journal

Abstract

Keywords