Andaliman (Zanthoxylum acanthopodium DC.) a herbal medicine from North Sumatera, Indonesia: Phytochemical and pharmacological review

Abstract

Andaliman (Z. acanthopodium DC) is a kind of flowering plant that belongs to the Rutaceae family. The habitats are found in southwestern China (Guangxi, Guizhou, Sichuan, Tibet, and Yunnan), Bangladesh, Bhutan, northern India, and northeastern India (Arunachal Pradesh, Assam, Manipur, Meghalaya, Nagaland, Sikkim, Uttar Pradesh, and West Bengal), Nepal, Laos, Burma, Vietnam, North Sumatra highlands, Peninsular Malaysia, and northern Thailand. Andaliman is indigenous to North Sumatra, more specifically the Toba Samosir District, North Tapanuli, and the Dairi region. The phytochemical investigation showed some terpenoids as well as other compounds such as alkaloids, flavonoids, glycosides, tannins, and saponins, but they have not been entirely identified. In Indonesia, the plant is employed both in the culinary industry as an additive for flavoring food and in the traditional medical system for treating various diseases. It was reported to possess antibacterial, antifungal, anti-inflammatory, anticancer, cardioprotective, hepatoprotective, nephroprotective, and wound healing properties, alongside other activities related to pregnancy that were tested in vitro and in vivo. The results of the investigation were based on previously published studies. This review serves as information and a summary, thereby making further exploration of Andaliman to be easier.

Keywords

• Andaliman
• Zanthoxylum acanthopodium DC
• Phytochemistry
• Pharmacology