Nature Communications (Sep 2020)
Integration of molecular profiles in a longitudinal wellness profiling cohort
- Abdellah Tebani,
- Anders Gummesson,
- Wen Zhong,
- Ina Schuppe Koistinen,
- Tadepally Lakshmikanth,
- Lisa M. Olsson,
- Fredrik Boulund,
- Maja Neiman,
- Hans Stenlund,
- Cecilia Hellström,
- Max J. Karlsson,
- Muhammad Arif,
- Tea Dodig-Crnković,
- Adil Mardinoglu,
- Sunjae Lee,
- Cheng Zhang,
- Yang Chen,
- Axel Olin,
- Jaromir Mikes,
- Hanna Danielsson,
- Kalle von Feilitzen,
- Per-Anders Jansson,
- Oskar Angerås,
- Mikael Huss,
- Sanela Kjellqvist,
- Jacob Odeberg,
- Fredrik Edfors,
- Valentina Tremaroli,
- Björn Forsström,
- Jochen M. Schwenk,
- Peter Nilsson,
- Thomas Moritz,
- Fredrik Bäckhed,
- Lars Engstrand,
- Petter Brodin,
- Göran Bergström,
- Mathias Uhlen,
- Linn Fagerberg
Affiliations
- Abdellah Tebani
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Anders Gummesson
- Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg
- Wen Zhong
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Ina Schuppe Koistinen
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Tadepally Lakshmikanth
- Science for Life Laboratory, Department of Women’s and Children’s Health, Karolinska Institutet
- Lisa M. Olsson
- Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg
- Fredrik Boulund
- Center for Translational Microbiome Research, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet
- Maja Neiman
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Hans Stenlund
- Swedish Metabolomics Centre, Department of Molecular Biology, Umeå University
- Cecilia Hellström
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Max J. Karlsson
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Muhammad Arif
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Tea Dodig-Crnković
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Adil Mardinoglu
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Sunjae Lee
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Cheng Zhang
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Yang Chen
- Science for Life Laboratory, Department of Women’s and Children’s Health, Karolinska Institutet
- Axel Olin
- Science for Life Laboratory, Department of Women’s and Children’s Health, Karolinska Institutet
- Jaromir Mikes
- Science for Life Laboratory, Department of Women’s and Children’s Health, Karolinska Institutet
- Hanna Danielsson
- Center for Translational Microbiome Research, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet
- Kalle von Feilitzen
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Per-Anders Jansson
- Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg
- Oskar Angerås
- Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg
- Mikael Huss
- Codon Consulting
- Sanela Kjellqvist
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Jacob Odeberg
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Fredrik Edfors
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Valentina Tremaroli
- Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg
- Björn Forsström
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Jochen M. Schwenk
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Peter Nilsson
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Thomas Moritz
- Swedish Metabolomics Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
- Fredrik Bäckhed
- Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg
- Lars Engstrand
- Center for Translational Microbiome Research, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet
- Petter Brodin
- Science for Life Laboratory, Department of Women’s and Children’s Health, Karolinska Institutet
- Göran Bergström
- Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg
- Mathias Uhlen
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- Linn Fagerberg
- Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology
- DOI
- https://doi.org/10.1038/s41467-020-18148-7
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 14
Abstract
An important aspect of precision medicine is to probe the stability in molecular profiles among healthy individuals over time. Here, the authors sample a longitudinal wellness cohort and analyse blood molecular profiles as well as gut microbiota composition.
