Outcome of Acute Viral Hepatitis in Children admitted in Tertiary Care Hospital of Ahmedabad, Gujarat

Abstract

Introduction: Viral hepatitis is a major health problem in both developing countries. Caused mainly by 5 hepatotropic viruses designated as hepatitis A, B, C, D, E. The present study was aimed to study the impact of various epidemiological factors, to compare the etiological profile of common viral agents and to study the outcome of children admitted with acute viral hepatitis. Methodology: This was a hospital based cross sectional study. All the children admitted in paediatric ward with symptoms of acute viral hepatitis during the study period were enrolled in the study. In this study data collected. Patients were treated according to protocol and final outcome was recorded. Results: Out of total 150 patients, maximum numbers of patients (45.33%) were less than 5 years of age and 108 (72%) were male. Most common complication was Fulminant Hepatic Failure (20%). Other complications were encephalopathy (5.33%), acute kidney injury (4%), DIC (2.67%) and spontaneous bacterial peritonitis (1.33%). Out of total 150, 142 (94.67%) were discharged suggesting acute viral hepatitis infection has good outcome. Conclusion: From the present study we concluded that fulminant hepatic failure due to hepatitis A virus is more common at younger age with high mortality. Safe drinking water and food and early active immunization may reduce mortality and improve outcome.

Keywords

• Viral Hepatitis
• Fulminant Hepatic Failure
• DIC
• Acute Kindly Injury
• SBP