G3: Genes, Genomes, Genetics (Feb 2022)

Population divergence time estimation using individual lineage label switching

  • Peter Beerli,
  • Haleh Ashki,
  • Somayeh Mashayekhi,
  • Michal Palczewski

DOI
https://doi.org/10.1093/g3journal/jkac040
Journal volume & issue
Vol. 12, no. 4

Abstract

Read online

AbstractDivergence time estimation from multilocus genetic data has become common in population genetics and phylogenetics. We present a new Bayesian inference method that treats the divergence time as a random variable. The divergence time is calculated from an assembly of splitting events on individual lineages in a genealogy. The time for such a splitting event is drawn from a hazard function of the truncated normal distribution. This allows easy integration into the standard coalescence framework used in programs such as MigrateMigrateIMa2pMigrate