Relationship between Mean platelet volume and recurrent miscarriage

Abstract

Introduction Recurrent pregnancy loss is identified by an ultrasound or histopathological test as two or more losses. Mean platelet volume (MPV) is the calculation of the average size of platelets and platelet activation. Aim The aim was to illuminate the etiopathogenesis of recurrent abortion, the study investigated the relationship between mean platelet size and recurrent abortion. Materials and methods This prospective research was performed at Al Zahraa University Hospital in Gynecology and Obstetrics Department and the General Kafer Alzyat Hospital. This study included 120 pregnant women in first trimester coming for antenatal care. All patients were tested with diagnostic testing for etiology of repeated abortion. All patients were evaluated for complete blood count parameters, including hemoglobin number, distance of distribution of red cells, mean corpuscular volume, white blood cells, platelets, and MPV. Results This analysis revealed that there is no statistically important difference between the groups analyzed regarding the mean age, BMI, blood pressure, and gestational age, as the mean age of studied group was 27.25±4.73 years compared with 26.77±5.26 years in the control group, and BMI in the studied group was 26.86±3.21 compared with 28.95±8.88 in the control group. There is a highly significant difference between studied and control groups regarding MPV. Conclusion In this research, the MPV values in women with repeated pregnancy loss were significantly higher than in the control group, which supports the importance of thromboembolic events.

Keywords

• abortion
• mean platelet volume
• thrombophilia