BMJ Open (Apr 2023)
National trends in the outcomes of subarachnoid haemorrhage and the prognostic influence of stroke centre capability in Japan: retrospective cohort study
- ,
- Satoshi Suzuki,
- Kenji Yamamoto,
- Hiroaki Tanaka,
- Hiroshi Ozawa,
- Yuji Okamoto,
- Tatsuya Abe,
- Hidenori Suzuki,
- Akiko Kada,
- Shigeki Nishino,
- Nobuyuki Sakai,
- Kunihiro Nishimura,
- Tomoyoshi Oikawa,
- Takanari Kitazono,
- Hiroshi Tanaka,
- Daisuke Onozuka,
- Akihito Hagihara,
- Hiroshi Ooyama,
- Akira Watanabe,
- Shinichi Yoshimura,
- Toru Iwama,
- Hiroki Sato,
- Satoshi Ushikoshi,
- Kiyohiro Houkin,
- Nobuhiro Mikuni,
- Naoyuki Nakao,
- Michio Nakamura,
- Nanako Tamiya,
- Naofumi Isono,
- Koji Iihara,
- Yutaka Yamaguchi,
- Kuniaki Ogasawara,
- Osamu Onodera,
- Yusaku Nakamura,
- Naoki Hayashi,
- Akira Takada,
- Hiroyuki Arai,
- Masayuki Ezura,
- Akio Hyodo,
- Shigeru Miyachi,
- Susumu Miyamoto,
- Yuji Matsumaru,
- Ichiro Nakahara,
- Tomoaki Terada,
- Kazunari Yoshida,
- Ai Kurogi,
- Ataru Nishimura,
- Yoshiaki Shiokawa,
- Koichi Arimura,
- Kaoru Kurisu,
- Fusao Ikawa,
- Kenji Ohata,
- Kyoichi Nomura,
- Nobuhito Saito,
- Hiroaki Fujiwara,
- Susumu Suzuki,
- Masanori Isobe,
- Soshiro Ogata,
- Takeshi Matsuoka,
- Junichiro Satomi,
- Takashi Matsumoto,
- Hiroyuki Nakase,
- Yasunari Niimi,
- Manabu Kinoshita,
- Mamoru Murakami,
- Masaaki Uno,
- Junichi Iida,
- Takashi Matsuoka,
- Tatsuya Sasaki,
- Shinichi Wakabayashi,
- Hiroki Toda,
- Hideki Sakai,
- Hajime Ohta,
- Osamu Yamamura,
- Hideyuki Ohnishi,
- Hiroko Oyama,
- Junichi Ono,
- Izumi Nagata,
- Hiroharu Kataoka,
- Ryota Kurogi,
- Hajime Arai,
- Atsuo Yoshino,
- Tsuyoshi Ohta,
- Hiroshi Sugimori,
- Hidehiro Hirabayashi,
- Hiroyuki Masaoka,
- Satoshi Yamamoto,
- Hideki Murakami,
- Kazuhiko Nozaki,
- Hiroyuki Matsumoto,
- Yuichiro Tanaka,
- Takahisa Mori,
- Keizo Yasui,
- Akira Takahashi,
- Ichiro Suzuki,
- Sachio Suzuki,
- TAKASHI YOSHIDA,
- Masanori Morimoto,
- Tetsuya Ueba,
- Hiromu Hadeishi,
- Masaki Chin,
- Michihiro Kohno,
- Hitoshi Fukuda,
- Toru Nishi,
- Kazunari Koga,
- Toshihiko Wakabayashi,
- Hiroki Ohkuma,
- Kazuhiro Hongo,
- Hiroshi Nakane,
- Kazumi Nitta,
- Satoshi Utsuki,
- Toshihiko Iuchi,
- Nice Ren,
- Hidefuku Gi,
- Kensuke Kawai,
- Masayuki Ishihara,
- Eiji Kohmura,
- Yoshihiro Nishiura,
- Kazutaka Yatsushiro,
- Kensaku Yoshida,
- Atsushi Tominaga,
- Masayuki Sumida,
- Hidenori Yoshida,
- Atsushi Sato,
- Takashi Inoue,
- Hiroaki Shimizu,
- Eiichiro Kamatsuka,
- Makoto Ichinose,
- Naoya Takeda,
- Tsuyoshi Inoue,
- Hidekazu Takahashi,
- Satoshi Kuroda,
- Toshiaki Osato,
- Nobutaka Horie,
- Isao Date,
- Yoichiro Hashimoto,
- Haruhiko Hoshino,
- Takafumi Shimogawa,
- Koji Yoshimoto,
- Teiji Tominaga,
- Isao Sasaki,
- Kazuo Kitazawa,
- Minoru Saitoh,
- Hitoshi Saito,
- Minoru Asahi,
- Makoto Goda,
- Atsuhito Takemura,
- Masaaki Shibukawa,
- Isao Fuwa,
- Saburo Watanabe,
- Seiko Kataoka,
- Koji Takasaki,
- Kouji Shiga,
- Kensuke Hayashida,
- Ryunosuke Uranishi,
- Chiaki Ito,
- Kenji Wakui,
- Takashi Saegusa,
- Isao Kitahara,
- Yasushi Ejima,
- Satoru Hayashi,
- Kazuyoshi Hattori,
- Shinji Okita,
- Toshikazu Ichihashi,
- Tsugumichi Ichioka,
- Shinichi Shirakami,
- Teruo Kimura,
- Tomonori Kobayashi,
- Kanehisa Kohno,
- Kazunori Yamanaka,
- Akira Morooka,
- Nozomi Mori,
- Hideo Kunimine,
- Masahiro Satoh,
- Syougo Imae,
- Hirochiyo Wada,
- Masanori Kabuto,
- Katsuyuki Hirakawa,
- Isao Inoue,
- Kiyoshi Kazekawa,
- Masani Nonaka,
- Kouzou Fukuyama,
- Shigenari Kin,
- Kiyoshi Saito,
- Yoichi Watanabe,
- Tadashi Arisawa,
- Kou Takahashi,
- Tetsuya Tanigawara,
- Junki Ito,
- Kei Hisada,
- Makoto Takeda,
- Jun Niwa,
- Mikio Nishiya,
- Shuji Hayashi,
- Ichiro Fujishima,
- Teiji Nakayama,
- Yoshihiko Watanabe,
- Koichirou Matsukado,
- Takamichi Yuguchi,
- Tadahisa Shono,
- Hiroyuki Nishimura,
- Jyunya Hayashi,
- Keisuke Migita,
- Kazuhiro Yokoyama,
- Hirotoshi Ohtaka,
- Takata Hisashi,
- Takamitsu Uchizawa,
- Naoki Shinohara,
- Mitsunobu Kaijima,
- Junkoh Yamamoto,
- Yoshio Sakagami,
- Hideo Aihara,
- Takayuki Sakaki,
- Keishi Fujita,
- Sumio Kobayashi,
- Nobuaki Momozaki,
- Masahito Hara,
- Akazi Kazunori,
- Fumitaka Miya,
- Hisato Minamide,
- Shinichiro Kurokawa,
- Syuichi Ishikawa,
- Naohisa Miura,
- Shinya Noda,
- Shoji Mashiyama,
- Shinji Amano,
- Takayuki Sugawara,
- Yukihiko Shimizu,
- Keiichi Saito,
- Kazuyuki Miura,
- Akinori Yabuta,
- Tatumi Yamanome,
- Hiroshi Seto,
- Makoto Hasebe,
- Hikaru Mizobuchi,
- Junkoh Sasaki,
- Shin Tsuruoka,
- Keiichi Nishimaki,
- Katsumi Takizawa,
- Hitoshi Tsugu,
- Nozomi Suzuki,
- Takeshi Kohno,
- Shu Hasegawa,
- Ken Asakura,
- Masaki Miyatake,
- Hiromu Konno,
- Katsunobu Takenaka,
- Akira Ikeda,
- Keizou Yamamoto,
- Keigo Matsumoto,
- Satoshi Inoha,
- Masaki Morisige,
- Kunihiko Harada,
- Hirofumi Hiyama,
- Yasuaki Takeda,
- Taturou Mori,
- Takekazu Akiyama,
- Osamu Okuda,
- Kazuaki Awamori,
- Naoki Shirasaki,
- Kimihiro Yoshino,
- Atsushi Shindo,
- Kazuho Hirahara,
- Shunichi Tanaka,
- Teruaki Kawano,
- Kazunori Arita,
- Hiroaki Sawaura,
- Yoichi Uozumi,
- Masahiko Tanaka,
- Shunsuke Shiraga,
- Shuji Sato,
- Mitsutoshi Nakada,
- Kimihisa Kinoshita,
- Nakazawa Kazutomo,
- Yasuhiro Fujimoto,
- Kunikazu Yoshimura,
- Masaaki Iwase,
- Shinichi Yagi,
- Atsushi Tsuchiya,
- Junichi Harashina,
- Sadao Kaneko,
- Naoto Kuwayama,
- Junya Hayashi,
- Masayuki Sasou,
- Sotaro Higashi,
- Masakazu Kitahara,
- Sumio Suda,
- Amami Kato,
- Satoshi Magarisawa,
- Kenji Hashimoto,
- Hirotoshi Hamaguchi,
- Tomohiko Satou,
- Masaru Idei,
- Haruhisa Tsukamoto,
- Toshihiro Kumabe,
- Naoaki Sato,
- Yasuyuki Toba,
- Takashi Tominaga,
- Haruo Yamashita,
- Toyoaki Shinohara,
- Kazuyoshi Watanabe,
- Hidenori Endo,
- Kenjirou Hujiwara,
- Toshinori Hasegawa,
- Hisashi Nitta,
- Kuroyanagi Takayuki,
- Nobuhiko Mizutani,
- Akira Tsunoda,
- Fumio Suzuki,
- Tetsuya Morimoto,
- Takuya Kawai,
- Mitsuyuki Fujitsuka,
- Hiromasa Tsuiki,
- Junichi Kuratsu,
- Hidemichi Sasayama,
- Shigehiro Ohmori,
- Seiko Hasegawa,
- Kazuhiro Kikuchi,
- Motohiro Morioka,
- Masayuki Yokota,
- Nozomu Murai,
- Yasumasa Yamamoto,
- Nobuhito Mori,
- Minoru Kidooka,
- Hiroshi Tenjin,
- Yoshihiro Iwamoto,
- Hitonori Takaba,
- Sei Haga,
- Yoshinori Arai,
- Toshiyuki Tsukada,
- Hirohide Karasudani,
- Masakazu Suga,
- Kawamoto Yukihiko,
- Naoto Izumi,
- Youtarou Takeuchi,
- Motohiro Arai,
- Shinji Okumura,
- Hisashi Tanaka,
- Yasushi Shibata,
- Tetsuya Masaoka,
- Masahiko Kasai,
- Hitoshi Miyake,
- Osamu Hamasaki,
- Misao Nishikawa,
- Naohiko Kubo,
- Yosimasa Kinosita,
- Hiroyuki Kaidu,
- Tarou Komuro,
- Hiroaki Shigeta,
- Yoshikazu Kusano,
- Shigekazu Takeuchi,
- Takayuki Matsuo,
- Yoshiharu Tokunaga,
- Norimoto Nakahara,
- Nobukazu Hashimoto,
- Mitsuhito Mase,
- Junpei Yoshimoto,
- Jin Momoji,
- Kenji Kamiyama,
- Koji Oka,
- Hiromichi Koga,
- Kazuya Morimoto,
- Tsutomu Kadekaru,
- Naoki Tokumitsu,
- Yasuyuki Nagai,
- Hirokazu Tanno,
- Takato Kagawa,
- Masaaki Saiki,
- Kotaro Ogihara,
- Junichi Imamura,
- Katsuhiro Yamashita,
- Akira Nakamizo,
- Yoshinari Nakamura,
- Ei-Ichirou Urasaki,
- Noriyuki Suzaki,
- Chiaki Takahashi,
- Youichirou Namba,
- Kazuo Hashikawa,
- Tomonori Yamada,
- Kazuyuki Kuwayama,
- Keiichi Sakai,
- Katsuhiro Kuroda,
- Hideyuki Kurihara,
- Masayuki Miyazono,
- Kosuke Miyahara,
- Hideaki Takahashi,
- Akihiko Saito,
- Igarashi Michitoku,
- Mitsuo Kouno,
- Shiro Kobayashi,
- Shunichi Yoneda,
- Hiroshi Kusunoki,
- Hiroji Miyake,
- Toshio Yokoe,
- Tatsuya Nakamura,
- Takayuki Kubodera,
- Mitsuhiko Hokari,
- Yasunari Otawara,
- Cheho Park,
- Hidemitu Nakagawa,
- Souichi Obara,
- Haruki Takahashi,
- Masafumi Ohtaki,
- Atsuya Okubo,
- Katsuhiko Hayashi,
- Masahisa Kawakami,
- Yu Takeda,
- Akihiko Kaga,
- Ryoichi Hayashi,
- Koji Tokunaga,
- Hiroyuki Nakashima,
- Yasuyuki Miyoshi,
- Atusi Kimoto,
- Toshimitsu Uchihara,
- Tomoaki Nagamine,
- Masahiro Noha,
- Hiromichi Sadashima,
- Toshihiko Kinjo,
- Osamu Tao,
- Masayuki Nakajima,
- Akira Isoshima,
- Kouichi Kuramoto,
- Shigeru Daido,
- Yoshiyasu Iwai,
- Toshihiko Kuroiwa,
- Akatsuki Wakayama,
- Kohsuke Yamashita,
- Yasunobu Gotou,
- Kouich Iwatsuki,
- Yoshida Masahiro,
- Nobuaki Kobayasi,
- Yoshimasa Niiya,
- Syouji Mabuchi,
- Motohiro Takayama,
- Kazuo Yamamoto,
- Junta Moroi,
- Masato Sugitani,
- Akio Ookura,
- Naoko Fujimura,
- Osamu Nishizaki,
- Sumio Isimaru,
- Hiroshi Wanihuchi,
- Nobukuni Murakami,
- Hiroto Murata,
- Naoki Kitagawa,
- Katsuhiko Kono,
- Michiya Kubo,
- Masashi Nakatsukasa,
- Makoto Inaba,
- Hidetoshi Ooigawa,
- Atsuhiro Kojima,
- Takamitsu Fujimaki,
- Osamu Fukuda,
- Yoshikazu Nakajima,
- Kazuyuki Kouno,
- Takaaki Yoshida,
- Reizou Kanemaru,
- Yohei Kudoh,
- Toshitaka Nakamura,
- Masayoshi Takigami,
- Shogo Nishi,
- Rokuya Tanikawa,
- Seisaburo Sakamoto,
- Makio Kaminogo,
- Seiichiro Hoshi,
- Yoshinari Okumura,
- Shinichi Okabe,
- Haruhiko Sato,
- Shiro Miyata,
- Kotaro Tsumura,
- Hiroshi Karibe,
- Noriaki Watabe,
- Ryuji Nakamura,
- Norifumi Shimoeda,
- Tsutomu Hitotsumatsu,
- Tomoaki Kameda,
- Hiroshi Ishiguchi,
- Atsuo Shinoda,
- Masanobu Hokama,
- Akinori Yamamura,
- Takeshi Kondoh,
- Kenichi Murao,
- Takafumi Wataya,
- Seiji Fukazawa,
- Shinsuke Muraoka,
- Hirosuke Fujisawa,
- Tsuneo Shishido,
- Mayumi Mori,
- Arai Hiroaki,
- Shinjitsu Nishimura,
- Zenichiro Watanabe,
- Susumu Nakashima,
- Kazuhito Nakamura,
- Yukinari Kakizawa,
- Hiroki Takano,
- Norihito Shirakawa,
- Masahiro Kagawa,
- Eiichiro Mabuchi,
- Kazusige Maeno,
- Takayuki Koizumi,
- Warou Taki,
- Yusuke Nakagaki,
- Kazuyuki Tane,
- Hiromichi Ooishi,
- Katsuyuki Asaoka,
- Yoshinori Akiyama,
- Tadao Kawamura,
- Atumi Takenobu,
- Takehisa Tuji,
- Masami Shimoda,
- Mitsunori Matsumae,
- Shinji Noda,
- Koiti Moroki,
- Hirofumi Oka,
- Masahito Agawa,
- Hajimu Miyake,
- Masateru Katayama,
- Shinichi Numazawa,
- Taketoshi Maehara,
- Hiroyuki Jimbo,
- Satoshi Ihara,
- Koji Matuoka,
- Oikawa Akihiro,
- Takahiro Oota,
- Makoto Noguchi,
- Takakazu Kawamata,
- Youichi Hashimoto,
- Keiichirou Onitsuka,
- Masahiko Kitano,
- Jae-Hyun Son,
- Toru Masuoka,
- Naoki Koketsu,
- Keiichi Akatsuka,
- Masamichi Kurosaki,
- Miyamori Tadao,
- Hiroaki Hondo,
- Kazumasa Yamatani,
- Hirofumi Oyama,
- Junji Koyama,
- Ogura Koichiro,
- Shinji Yamamoto,
- Hitoshi Tabata,
- Kazuya Uemura,
- Kazuhiko Sato,
- Hideyuki Yoshida,
- Takafumi Nishizaki,
- Hiroshi Egami,
- Hideo Takeshima,
- Shogo Ishiuchi,
- Akira Matsumura,
- Hiroyuki Kinouchi,
- Susumu Mekaru,
- Mikihiko Takeshita,
- Hitoshi Ozawa,
- Kiichiro Zenke,
- Takeshi Matsuyama,
- Toshikazu Kuwata,
- Teruyuki Habu,
- Tomoyoshi Okumura,
- Seiya Takehara,
- Rei Kondo,
- Takashi Kumagai,
- Keiten So,
- Sunao Takemura,
- Sonoda Yukihiko,
- Manabu Urakawa,
- Yasuhiro Hamada,
- Michiyasu Suzuki,
- Mikito Uchida,
- Hidehito Koizumi,
- Masaru Yamada,
- Takashi Tsuruno,
- Gen Ishida,
- Ryouichi Masuda,
- Makoto Kimura,
- Shinichirou Ishihara,
- Masashi Morikawa,
- Hidetoshi Murata,
- Katsumi Sakata,
- Motohiro Nomura,
- Akihiro Nemoto,
- Sumio Endou,
- Nobuo Hirota,
- Kennji Itou,
- Hiroaki Minami,
- Yoshihumi Teramoto
Affiliations
- 1 School of Nursing, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada
- Satoshi Suzuki
- Department of Neuropathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Kenji Yamamoto
- 1 Clinical Research Center and Department of Neurology, Utano National Hospital, Kyoto, Japan
- Hiroaki Tanaka
- 1 Department of Hematology, Asahi General Hospital, Asahi, Chiba, Japan
- Hiroshi Ozawa
- 6 Department of Pediatrics, Shimada Ryoiku Center Hachiouji, Tokyo, Japan
- Yuji Okamoto
- 1 Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
- Tatsuya Abe
- 1 Department of Neurosurgery, Faculty of Medicine, Saga University, Saga, Japan
- Hidenori Suzuki
- 2 Department of Neurosurgery, Mie University Graduate School of Medicine, Tsu, Japan
- Akiko Kada
- 2 Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan
- Shigeki Nishino
- Department of Neurological Surgery, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan
- Nobuyuki Sakai
- Department of Neurosurgery, Kobe City General Hospital, Kobe, Japan
- Kunihiro Nishimura
- Department of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Suita, Japan
- Tomoyoshi Oikawa
- 12 Department of Neurosurgery, Minamisoma Municipal General Hospital, Minamisoma, Fukushima, Japan
- Takanari Kitazono
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Hiroshi Tanaka
- Department of Internal Medicine, Niigata Cancer Center Hospital, Niigata, Japan
- Daisuke Onozuka
- Department of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Suita, Japan
- Akihito Hagihara
- Department of Health Communication, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Hiroshi Ooyama
- 14 Ryougoku East Gate Clinic, Tokyo, Japan
- Akira Watanabe
- Research Division for Development of Anti-Infective Agents, Tohoku Bunka Gakuen University, Miyagi, Japan
- Shinichi Yoshimura
- 15 Department of Neurosurgery, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
- Toru Iwama
- 2 Department of Neurosurgery, Gifu University Graduate School of Medicine, Gifu, Japan
- Hiroki Sato
- Department of Medical Affairs, Shionogi & Co, Ltd, Osaka, Japan
- Satoshi Ushikoshi
- 2 Department of Neurosurgery, Hokkaido Medical Center, Sapporo, Japan
- Kiyohiro Houkin
- 1 Department of Neurosurgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan
- Nobuhiro Mikuni
- Neurosurgery, Sapporo Medical University, Sapporo, Hokkaido, Japan
- Naoyuki Nakao
- 2 Wakayama Medical University School of Medicine Graduate School of Medicine, Department of Neurological Surgery, Wakayama, Japan
- Michio Nakamura
- 1 Department of Gastroenterology, Sapporo City General Hospital, Sapporo, Japan
- Nanako Tamiya
- Health Services Research, University of Tsukuba, Tsukuba, Japan
- Naofumi Isono
- 1 Department of Neurosurgery, Higashisumiyoshi Morimoto Hospital, Osaka, Japan
- Koji Iihara
- Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Yutaka Yamaguchi
- 1 Department of Emergency Medicine, Okinawa Prefectural Chubu Hospital, Uruma, Okinawa, Japan
- Kuniaki Ogasawara
- Department of Neurosurgery, School of Medicine, Iwate Medical University, Morioka, Japan
- Osamu Onodera
- 1 Department of Neurology, Clinical Neuroscience Branch, Brain Research Institute, Niigata University, Niigata, Japan
- Yusaku Nakamura
- Naoki Hayashi
- Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan
- Akira Takada
- Department of Radiology, Toyohashi Municipal Hospital, Toyohashi, Aichi, Japan
- Hiroyuki Arai
- 1 Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan
- Masayuki Ezura
- Akio Hyodo
- Shigeru Miyachi
- 6 Neuroendovascular Therapy Centre, Aichi Medical University, Aichi-gun, Japan
- Susumu Miyamoto
- 2Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
- Yuji Matsumaru
- 8 Division of Stroke Prevention and Treatment, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
- Ichiro Nakahara
- Department of Comprehensive Strokology, Fujita Health University, Toyoake, Aichi, Japan
- Tomoaki Terada
- Neurosurgery, Showa University Fujigaoka Hospital, Yokohama, Japan
- Kazunari Yoshida
- Department of Neurosurgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan
- Ai Kurogi
- Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Ataru Nishimura
- Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Yoshiaki Shiokawa
- Department of Neurosurgery, Kyorin University School of Medicine, Tokyo, Japan
- Koichi Arimura
- Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Kaoru Kurisu
- Department of Neurosurgery, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan
- Fusao Ikawa
- Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan
- Kenji Ohata
- professor
- Kyoichi Nomura
- 5 Department of Neurology, Saitama Medical Center, Kawagoe, Saitama, Japan
- Nobuhito Saito
- Department of Neurosurgery, The University of Tokyo, Bunkyo-ku, Tokyo, Japan
- Hiroaki Fujiwara
- 1 Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
- Susumu Suzuki
- Masanori Isobe
- Department of Psychiatry, Graduate School of Medicine, Kyoto University, Kyoto, Japan
- Soshiro Ogata
- Department of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan
- Takeshi Matsuoka
- Department of Neurology, Date Red Cross Hospital, Date, Hokkaido, Japan
- Junichiro Satomi
- Department of Neurosurgery, Tokushima University Hospital, Tokushima, Tokushima, Japan
- Takashi Matsumoto
- Department of Gynecology, Sikoku Cancer Center, Ehime; and
- Hiroyuki Nakase
- 1 Department of Neurosurgery, Nara Medical University School of Medicine Graduate School of Medicine, Kashihara, Nara, Japan
- Yasunari Niimi
- Neuroendovascular Therapy, St. Luke`s International Hospital, Chuo-ku, Tokyo, Japan
- Manabu Kinoshita
- Neurosurgery, Osaka International Cancer Institute, Osaka, Japan
- Mamoru Murakami
- 77 Neurosurgery, Kyoto Second Red Cross Hospital, Kyoto, Japan
- Masaaki Uno
- Junichi Iida
- 117 Neurosurgery, Osaka General Medical Center, Osaka, Japan
- Takashi Matsuoka
- 2Laboratory for Infectious Diseases, Tokai University School of Medicine, Isehara City, Japan
- Tatsuya Sasaki
- Shinichi Wakabayashi
- Hiroki Toda
- 1 Neurosurgery, Japanese Red Cross Fukui Hospital, Fukui, Japan
- Hideki Sakai
- 2Department of Rehabilitation, Kobe City Medical Center West Hospital, Kobe, Hyogo, Japan
- Hajime Ohta
- Department of Gastroenterology, National Hospital Organization, Kanazawa Medical Center, Kanazawa, Japan
- Osamu Yamamura
- 3Department of Community Health Care Promotion, University of Fukui Hospital, Fukui Prefecture, Japan
- Hideyuki Ohnishi
- Ohnishi Neurological Center, Akashi, Japan
- Hiroko Oyama
- Junichi Ono
- 6Chiba Cardiovascular Center, Chiba, Japan
- Izumi Nagata
- 10Kokura Memorial Hospital, Fukuoka, Japan
- Hiroharu Kataoka
- 14Department of Neurosurgery, National Cerebral and Cardiovascular Center, Suita, Japan
- Ryota Kurogi
- Department of Neurosurgery, Fukuoka Tokushukai Medical Center, Kasuga, Fukuoka, Japan
- Hajime Arai
- 2Department of Neurosurgery, Juntendo University School of Medicine, Tokyo, Japan
- Atsuo Yoshino
- 3Department of Neurological Surgery, Nihon School of Medicine, Tokyo, Japan
- Tsuyoshi Ohta
- Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine, Yamagata;
- Hiroshi Sugimori
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Hidehiro Hirabayashi
- Hiroyuki Masaoka
- Satoshi Yamamoto
- Departments of Radiology, Hyogo College of Medicine, Hyogo, Japan.
- Hideki Murakami
- Division of Molecular Oncology, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Chikusa-Ku, Nagoya 464-8681, Japan
- Kazuhiko Nozaki
- Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
- Hiroyuki Matsumoto
- 1 Department of Neurological Surgery, Kishiwada Tokushukai Hospital, Osaka, Japan
- Yuichiro Tanaka
- 2Department of Health Policy and Management, University of Occupational and Environmental Health, Japan
- Takahisa Mori
- 3 Department of Stroke Treatment, Shonan Kamakura General Hospital Stroke Center, Kamakura, Japan
- Keizo Yasui
- 1Department of Neurology, Nagoya Daini Red Cross Hospital, Nagoya, Japan
- Akira Takahashi
- 1Department of Neurology, Nagoya Daini Red Cross Hospital, Nagoya, Japan
- Ichiro Suzuki
- Sachio Suzuki
- TAKASHI YOSHIDA
- Department of Urology and Andrology, Kansai Medical University, Osaka, Japan
- Masanori Morimoto
- 1Department of Neurosurgery, Kochi Health Sciences Center, Kochi City, Kochi Prefecture, Japan
- Tetsuya Ueba
- 2Department of Neurosurgery, Kochi Medical School, Nankoku City, Kochi Prefecture, Japan
- Hiromu Hadeishi
- 1Department of Neurosurgery, Kameda Medical Center, Kamogawa City, Chiba Prefecture, Japan
- Masaki Chin
- 1Department of Neurosurgery, Kurashiki Central Hospital, Kurashiki-City, Japan
- Michihiro Kohno
- Hitoshi Fukuda
- Department of Neurosurgery, Kochi Medical School, Nankoku, Japan
- Toru Nishi
- Department of Neurosurgery, Stroke Centre, Saiseikai Kumamoto Hospital, Kumamoto, Japan
- Kazunari Koga
- Department of Neurosurgery, Stroke Centre, Saiseikai Kumamoto Hospital, Kumamoto, Japan
- Toshihiko Wakabayashi
- 1Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
- Hiroki Ohkuma
- Department of Neurosurgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan
- Kazuhiro Hongo
- Hiroshi Nakane
- Kazumi Nitta
- Department of Neurosurgery, Hokuto Hospital, Obihiro, Hokkaido, Japan
- Satoshi Utsuki
- 2Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Japan
- Toshihiko Iuchi
- 1Division of Neurological Surgery, Chiba Cancer Centre, Chiba, Japan
- Nice Ren
- Department of Neurosurgery, Baba Memorial Hospital, Osaka, Japan
- Hidefuku Gi
- Department of Neurosurgery, Baba Memorial Hospital, Osaka, Japan
- Kensuke Kawai
- 1 Department of Neurosurgery, Jichi Medical University, Shimotsuke, Japan
- Masayuki Ishihara
- Department of Neurosurgery, National Hospital Organisation Tochigi Medical Center, Utsunomiya, Japan
- Eiji Kohmura
- 2Department of Neurosurgery, Kobe University School of Medicine, Kobe, Hyogo, Japan
- Yoshihiro Nishiura
- The First Department of Internal Medicine, Graduate School of Biomedical Science, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, Japan
- Kazutaka Yatsushiro
- Kensaku Yoshida
- 5Department of Neurosurgery, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan
- Atsushi Tominaga
- Department of Neurosurgery and Neuroendovascular Therapy, Hiroshima Prefectural Hospital, Hiroshima, Japan
- Masayuki Sumida
- Department of Neurosurgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan
- Hidenori Yoshida
- Department of Neurosurgery, Fukuoka Tokushukai Medical Center, Kasuga, Fukuoka, Japan
- Atsushi Sato
- Takashi Inoue
- Department of Internal Medicine, Sano Kosei General Hospital, Tochigi, Japan
- Hiroaki Shimizu
- Department of Neurosurgery, Akita University Graduate School of Medicine, Akita, Japan
- Eiichiro Kamatsuka
- Makoto Ichinose
- Naoya Takeda
- Tsuyoshi Inoue
- Department of Physiology of Visceral Function and Body Fluid, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
- Hidekazu Takahashi
- Department of Gastroenterological Surgery, Osaka University, Suita, Japan
- Satoshi Kuroda
- Department of Neurosurgery, Toyama University, Toyama, Japan
- Toshiaki Osato
- Department of Neurosurgery, Nakamura Memorial Hospital, Sapporo, Japan
- Nobutaka Horie
- Department of Neurosurgery, Hiroshima University Hospital, Hiroshima, Japan
- Isao Date
- Department of Neurological Surgery, Okayama University Graduate School of Medicine, Okayama, Japan
- Yoichiro Hashimoto
- Department of Neurology, Kumamoto City Hospital, Kumamoto, Japan
- Haruhiko Hoshino
- Department of Neurology, Tokyo Saiseikai Central Hospital, Tokyo, Japan
- Takafumi Shimogawa
- Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Koji Yoshimoto
- Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Teiji Tominaga
- Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan
- Isao Sasaki
- Kazuo Kitazawa
- Minoru Saitoh
- Hitoshi Saito
- Minoru Asahi
- Makoto Goda
- Atsuhito Takemura
- Masaaki Shibukawa
- Isao Fuwa
- Saburo Watanabe
- Seiko Kataoka
- Koji Takasaki
- Kouji Shiga
- Kensuke Hayashida
- Ryunosuke Uranishi
- Chiaki Ito
- Kenji Wakui
- Takashi Saegusa
- Isao Kitahara
- Yasushi Ejima
- Satoru Hayashi
- Kazuyoshi Hattori
- Shinji Okita
- Toshikazu Ichihashi
- Tsugumichi Ichioka
- Shinichi Shirakami
- Teruo Kimura
- Tomonori Kobayashi
- Kanehisa Kohno
- Kazunori Yamanaka
- Akira Morooka
- Nozomi Mori
- Hideo Kunimine
- Masahiro Satoh
- Syougo Imae
- Hirochiyo Wada
- Masanori Kabuto
- Katsuyuki Hirakawa
- Isao Inoue
- Kiyoshi Kazekawa
- Masani Nonaka
- Kouzou Fukuyama
- Shigenari Kin
- Kiyoshi Saito
- Yoichi Watanabe
- Tadashi Arisawa
- Kou Takahashi
- Tetsuya Tanigawara
- Junki Ito
- Kei Hisada
- Makoto Takeda
- Jun Niwa
- Mikio Nishiya
- Shuji Hayashi
- Ichiro Fujishima
- Teiji Nakayama
- Yoshihiko Watanabe
- Koichirou Matsukado
- Takamichi Yuguchi
- Tadahisa Shono
- Hiroyuki Nishimura
- Jyunya Hayashi
- Keisuke Migita
- Kazuhiro Yokoyama
- Hirotoshi Ohtaka
- Takata Hisashi
- Takamitsu Uchizawa
- Naoki Shinohara
- Mitsunobu Kaijima
- Junkoh Yamamoto
- Yoshio Sakagami
- Hideo Aihara
- Takayuki Sakaki
- Keishi Fujita
- Sumio Kobayashi
- Nobuaki Momozaki
- Masahito Hara
- Akazi Kazunori
- Fumitaka Miya
- Hisato Minamide
- Shinichiro Kurokawa
- Syuichi Ishikawa
- Naohisa Miura
- Shinya Noda
- Shoji Mashiyama
- Shinji Amano
- Takayuki Sugawara
- Yukihiko Shimizu
- Keiichi Saito
- Kazuyuki Miura
- Akinori Yabuta
- Tatumi Yamanome
- Hiroshi Seto
- Makoto Hasebe
- Hikaru Mizobuchi
- Junkoh Sasaki
- Shin Tsuruoka
- Keiichi Nishimaki
- Katsumi Takizawa
- Hitoshi Tsugu
- Nozomi Suzuki
- Takeshi Kohno
- Shu Hasegawa
- Ken Asakura
- Masaki Miyatake
- Hiromu Konno
- Katsunobu Takenaka
- Akira Ikeda
- Keizou Yamamoto
- Keigo Matsumoto
- Satoshi Inoha
- Masaki Morisige
- Kunihiko Harada
- Hirofumi Hiyama
- Yasuaki Takeda
- Taturou Mori
- Takekazu Akiyama
- Osamu Okuda
- Kazuaki Awamori
- Naoki Shirasaki
- Kimihiro Yoshino
- Atsushi Shindo
- Kazuho Hirahara
- Shunichi Tanaka
- Teruaki Kawano
- Kazunori Arita
- Hiroaki Sawaura
- Yoichi Uozumi
- Masahiko Tanaka
- Shunsuke Shiraga
- Shuji Sato
- Mitsutoshi Nakada
- Kimihisa Kinoshita
- Nakazawa Kazutomo
- Yasuhiro Fujimoto
- Kunikazu Yoshimura
- Masaaki Iwase
- Shinichi Yagi
- Atsushi Tsuchiya
- Junichi Harashina
- Sadao Kaneko
- Naoto Kuwayama
- Junya Hayashi
- Masayuki Sasou
- Sotaro Higashi
- Masakazu Kitahara
- Sumio Suda
- Amami Kato
- Satoshi Magarisawa
- Kenji Hashimoto
- Hirotoshi Hamaguchi
- Tomohiko Satou
- Masaru Idei
- Haruhisa Tsukamoto
- Toshihiro Kumabe
- Naoaki Sato
- Yasuyuki Toba
- Takashi Tominaga
- Haruo Yamashita
- Toyoaki Shinohara
- Kazuyoshi Watanabe
- Hidenori Endo
- Kenjirou Hujiwara
- Toshinori Hasegawa
- Hisashi Nitta
- Kuroyanagi Takayuki
- Nobuhiko Mizutani
- Akira Tsunoda
- Fumio Suzuki
- Tetsuya Morimoto
- Takuya Kawai
- Mitsuyuki Fujitsuka
- Hiromasa Tsuiki
- Junichi Kuratsu
- Hidemichi Sasayama
- Shigehiro Ohmori
- Seiko Hasegawa
- Kazuhiro Kikuchi
- Motohiro Morioka
- Masayuki Yokota
- Nozomu Murai
- Yasumasa Yamamoto
- Nobuhito Mori
- Minoru Kidooka
- Hiroshi Tenjin
- Yoshihiro Iwamoto
- Hitonori Takaba
- Sei Haga
- Yoshinori Arai
- Toshiyuki Tsukada
- Hirohide Karasudani
- Masakazu Suga
- Kawamoto Yukihiko
- Naoto Izumi
- Youtarou Takeuchi
- Motohiro Arai
- Shinji Okumura
- Hisashi Tanaka
- Yasushi Shibata
- Tetsuya Masaoka
- Masahiko Kasai
- Hitoshi Miyake
- Osamu Hamasaki
- Misao Nishikawa
- Naohiko Kubo
- Yosimasa Kinosita
- Hiroyuki Kaidu
- Tarou Komuro
- Hiroaki Shigeta
- Yoshikazu Kusano
- Shigekazu Takeuchi
- Takayuki Matsuo
- Yoshiharu Tokunaga
- Norimoto Nakahara
- Nobukazu Hashimoto
- Mitsuhito Mase
- Junpei Yoshimoto
- Jin Momoji
- Kenji Kamiyama
- Koji Oka
- Hiromichi Koga
- Kazuya Morimoto
- Tsutomu Kadekaru
- Naoki Tokumitsu
- Yasuyuki Nagai
- Hirokazu Tanno
- Takato Kagawa
- Masaaki Saiki
- Kotaro Ogihara
- Junichi Imamura
- Katsuhiro Yamashita
- Akira Nakamizo
- Yoshinari Nakamura
- Ei-Ichirou Urasaki
- Noriyuki Suzaki
- Chiaki Takahashi
- Youichirou Namba
- Kazuo Hashikawa
- Tomonori Yamada
- Kazuyuki Kuwayama
- Keiichi Sakai
- Katsuhiro Kuroda
- Hideyuki Kurihara
- Masayuki Miyazono
- Kosuke Miyahara
- Hideaki Takahashi
- Akihiko Saito
- Igarashi Michitoku
- Mitsuo Kouno
- Shiro Kobayashi
- Shunichi Yoneda
- Hiroshi Kusunoki
- Hiroji Miyake
- Toshio Yokoe
- Tatsuya Nakamura
- Takayuki Kubodera
- Mitsuhiko Hokari
- Yasunari Otawara
- Cheho Park
- Hidemitu Nakagawa
- Souichi Obara
- Haruki Takahashi
- Masafumi Ohtaki
- Atsuya Okubo
- Katsuhiko Hayashi
- Masahisa Kawakami
- Yu Takeda
- Akihiko Kaga
- Ryoichi Hayashi
- Koji Tokunaga
- Hiroyuki Nakashima
- Yasuyuki Miyoshi
- Atusi Kimoto
- Toshimitsu Uchihara
- Tomoaki Nagamine
- Masahiro Noha
- Hiromichi Sadashima
- Toshihiko Kinjo
- Osamu Tao
- Masayuki Nakajima
- Akira Isoshima
- Kouichi Kuramoto
- Shigeru Daido
- Yoshiyasu Iwai
- Toshihiko Kuroiwa
- Akatsuki Wakayama
- Kohsuke Yamashita
- Yasunobu Gotou
- Kouich Iwatsuki
- Yoshida Masahiro
- Nobuaki Kobayasi
- Yoshimasa Niiya
- Syouji Mabuchi
- Motohiro Takayama
- Kazuo Yamamoto
- Junta Moroi
- Masato Sugitani
- Akio Ookura
- Naoko Fujimura
- Osamu Nishizaki
- Sumio Isimaru
- Hiroshi Wanihuchi
- Nobukuni Murakami
- Hiroto Murata
- Naoki Kitagawa
- Katsuhiko Kono
- Michiya Kubo
- Masashi Nakatsukasa
- Makoto Inaba
- Hidetoshi Ooigawa
- Atsuhiro Kojima
- Takamitsu Fujimaki
- Osamu Fukuda
- Yoshikazu Nakajima
- Kazuyuki Kouno
- Takaaki Yoshida
- Reizou Kanemaru
- Yohei Kudoh
- Toshitaka Nakamura
- Masayoshi Takigami
- Shogo Nishi
- Rokuya Tanikawa
- Seisaburo Sakamoto
- Makio Kaminogo
- Seiichiro Hoshi
- Yoshinari Okumura
- Shinichi Okabe
- Haruhiko Sato
- Shiro Miyata
- Kotaro Tsumura
- Hiroshi Karibe
- Noriaki Watabe
- Ryuji Nakamura
- Norifumi Shimoeda
- Tsutomu Hitotsumatsu
- Tomoaki Kameda
- Hiroshi Ishiguchi
- Atsuo Shinoda
- Masanobu Hokama
- Akinori Yamamura
- Takeshi Kondoh
- Kenichi Murao
- Takafumi Wataya
- Seiji Fukazawa
- Shinsuke Muraoka
- Hirosuke Fujisawa
- Tsuneo Shishido
- Mayumi Mori
- Arai Hiroaki
- Shinjitsu Nishimura
- Zenichiro Watanabe
- Susumu Nakashima
- Kazuhito Nakamura
- Yukinari Kakizawa
- Hiroki Takano
- Norihito Shirakawa
- Masahiro Kagawa
- Eiichiro Mabuchi
- Kazusige Maeno
- Takayuki Koizumi
- Warou Taki
- Yusuke Nakagaki
- Kazuyuki Tane
- Hiromichi Ooishi
- Katsuyuki Asaoka
- Yoshinori Akiyama
- Tadao Kawamura
- Atumi Takenobu
- Takehisa Tuji
- Masami Shimoda
- Mitsunori Matsumae
- Shinji Noda
- Koiti Moroki
- Hirofumi Oka
- Masahito Agawa
- Hajimu Miyake
- Masateru Katayama
- Shinichi Numazawa
- Taketoshi Maehara
- Hiroyuki Jimbo
- Satoshi Ihara
- Koji Matuoka
- Oikawa Akihiro
- Takahiro Oota
- Makoto Noguchi
- Takakazu Kawamata
- Youichi Hashimoto
- Keiichirou Onitsuka
- Masahiko Kitano
- Jae-Hyun Son
- Toru Masuoka
- Naoki Koketsu
- Keiichi Akatsuka
- Masamichi Kurosaki
- Miyamori Tadao
- Hiroaki Hondo
- Kazumasa Yamatani
- Hirofumi Oyama
- Junji Koyama
- Ogura Koichiro
- Shinji Yamamoto
- Hitoshi Tabata
- Kazuya Uemura
- Kazuhiko Sato
- Hideyuki Yoshida
- Takafumi Nishizaki
- Hiroshi Egami
- Hideo Takeshima
- Shogo Ishiuchi
- Akira Matsumura
- Hiroyuki Kinouchi
- Susumu Mekaru
- Mikihiko Takeshita
- Hitoshi Ozawa
- Kiichiro Zenke
- Takeshi Matsuyama
- Toshikazu Kuwata
- Teruyuki Habu
- Tomoyoshi Okumura
- Seiya Takehara
- Rei Kondo
- Takashi Kumagai
- Keiten So
- Sunao Takemura
- Sonoda Yukihiko
- Manabu Urakawa
- Yasuhiro Hamada
- Michiyasu Suzuki
- Mikito Uchida
- Hidehito Koizumi
- Masaru Yamada
- Takashi Tsuruno
- Gen Ishida
- Ryouichi Masuda
- Makoto Kimura
- Shinichirou Ishihara
- Masashi Morikawa
- Hidetoshi Murata
- Katsumi Sakata
- Motohiro Nomura
- Akihiro Nemoto
- Sumio Endou
- Nobuo Hirota
- Kennji Itou
- Hiroaki Minami
- Yoshihumi Teramoto
- DOI
- https://doi.org/10.1136/bmjopen-2022-068642
- Journal volume & issue
-
Vol. 13,
no. 4
Abstract
Objectives To examine the national, 6-year trends in in-hospital clinical outcomes of patients with subarachnoid haemorrhage (SAH) who underwent clipping or coiling and the prognostic influence of temporal trends in the Comprehensive Stroke Center (CSC) capabilities on patient outcomes in Japan.Design Retrospective study.Setting Six hundred and thirty-one primary care institutions in Japan.Participants Forty-five thousand and eleven patients with SAH who were urgently hospitalised, identified using the J-ASPECT Diagnosis Procedure Combination database.Primary and secondary outcome measures Annual number of patients with SAH who remained untreated, or who received clipping or coiling, in-hospital mortality and poor functional outcomes (modified Rankin Scale: 3–6) at discharge. Each CSC was assessed using a validated scoring system (CSC score: 1–25 points).Results In the overall cohort, in-hospital mortality decreased (year for trend, OR (95% CI): 0.97 (0.96 to 0.99)), while the proportion of poor functional outcomes remained unchanged (1.00 (0.98 to 1.02)). The proportion of patients who underwent clipping gradually decreased from 46.6% to 38.5%, while that of those who received coiling and those left untreated gradually increased from 16.9% to 22.6% and 35.4% to 38%, respectively. In-hospital mortality of coiled (0.94 (0.89 to 0.98)) and untreated (0.93 (0.90 to 0.96)) patients decreased, whereas that of clipped patients remained stable. CSC score improvement was associated with increased use of coiling (per 1-point increase, 1.14 (1.08 to 1.20)) but not with short-term patient outcomes regardless of treatment modality.Conclusions The 6-year trends indicated lower in-hospital mortality for patients with SAH (attributable to better outcomes), increased use of coiling and multidisciplinary care for untreated patients. Further increasing CSC capabilities may improve overall outcomes, mainly by increasing the use of coiling. Additional studies are necessary to determine the effect of confounders such as aneurysm complexity on outcomes of clipped patients in the modern endovascular era.
