بیولوژی کاربردی (Mar 2020)
Effect of phytosterol and Bacillus coagulant probiotic in reducing blood cholesterol
Abstract
Target and background: In recent years, many studies have been conducted on high-risk factors for some blood lipids, which can lead to the development of cardiovascular diseases. The most important goal of this study is to investigate the effect of phytosterol and Bacillus coagulant probiotic on the reduction of blood cholesterol in adult rats. Material and Methods: 40 Male NMRI mice with a weight of 25-30g were used .The mouse were divided into 5 groups of 8, including: control group, HCD group (1% of the weight of the food consumed cholesterol diet), Experimental group 1 (daily, in addition to cholesterol diet, 0.1g of phytosterol Experimental group 2 (daily, in addition to cholesterol diet, 0.2g of Bacillus coagulant bacteria plus animal oil was gavaged), Experimental group 3 (daily, in addition to cholesterol diet, 0.1g combination of phytosterol and Bacillus coagulants probiotic were digested with germicidal oil). Sperry samples were taken from the blood samples at the end of the experiments, and cholesterol, triglycerides, HDL and LDL blood samples were measured and. Results: Cholesterol, triglyceride, HDL and LDL showed a significant decrease compared to the control group. Conclusion: According to the above results, it can be said that phytosterol and Bacillus coagulant probiotic simultaneously decrease blood lipids, and therefore, it is recommended to use this pump.