Green synthesis approach: Utilizing chrysanthemum extract as reducing and stabilizing agent for the fabrication of silver nanoparticles and their antimicrobial properties study

Abstract

This research explores the eco-friendly synthesis of silver nanoparticles (AgNPs) using Chrysanthemum extract, emphasizing its application in antimicrobial treatments. The study primarily focused on assessing the effect of extract concentration on nanoparticle characteristics. The synthesized AgNPs, at higher Chrysanthemum extract concentrations (up to 15%), exhibited a notable decrease in size, from 48.5 nm at 2% to 22.1 nm, and an increase in yield, achieving 2.24 mg/mL. The AgNPs showed a significant antibacterial effect, with the lowest IC50 value of 2.08 µg/mL against Vibrio cholerae, demonstrating a broad-spectrum efficacy. Advanced characterization techniques like SEM and FTIR spectroscopy confirmed the morphological integrity and phytochemical capping of the nanoparticles. The study successfully highlights the potential of Chrysanthemum extract not only as a sustainable source for nanoparticle synthesis but also in enhancing the biocompatibility and efficacy of AgNPs, paving the way for their application in medical and environmental fields.

Keywords

• Phytochemical reduction
• Nanoparticle biocompatibility
• Antimicrobial efficacy
• Eco-friendly nanotechnology
• Sustainable nanoparticle synthesis