Journal of Saudi Chemical Society (Dec 2019)
Nd(OTf)3-catalyzed intramolecular-intermolecular cascade cyclization reaction: An access to phenanthro[9,10-b]furan derivatives
Abstract
An intramolecular-intermolecular cascade cyclization reaction via multi metal-carbene intermediates has been developed. This reaction uses catalytic amount of Nd(OTf)3, which actives both alkyne and aldehyde moieties. This protocol provides a novel strategy for the synthesis of phenanthro[9,10-b]furans. Keywords: Phenanthro[9,10-b]furan, Cyclization, Neodymium, Heterocycle, Cascade reaction