Improved enzymatic resistance of rainbow trout (Oncorhynchus mykiss) with vitamin C during exposure to various concentrations of nanoparticles ZnO

Abstract

Zinc oxide nanoparticles can enter to body through breathing, skin and nourishment, and disrupt the physiology of the body. Ascorbic acid can act as a potent antioxidant to prevent the negative effects of nanoparticles. In this study, 170 individuals of rainbow trout with an average weight of 170 g were kept in 70 L tanks. Fish were exposed to concentrations of 40 and 80 mg.L-1 Nano-zinc oxide, and 400 and 800 mg.kg-1 vitamin C. After 10 days of exposure to 80 mg.L-1 Nano-zinc oxide and 800 mg.kg-1 vitamin C the liver enzyme activity was significantly lower than other treatments. Oral administration of vitamin C can improve the enzymatic parameters and reduce the harmful effects of zinc oxide nanoparticles on hepatic enzyme activity.

Keywords

• liver enzymes
• nano zinc oxide
• vitamin c