Regiospecific α-methylene functionalisation of tertiary amines with alkynes via Au-catalysed concerted one-proton/two-electron transfer to O2

Abstract

The selective α-methylene functionalization of tertiary amines is challenging. Here, the authors report the gold nanoparticles-catalyzed α-methylene alkynylation of tertiary amines via concerted one-proton/two-electron transfer to O2.