Electrochemical determination of adenosine by natural phosphate modified carbon paste electrode: Analytical application in serum

Abstract

In this study, a sensitive electrochemical voltammetry method for the analysis of extra cellular adenosine (AD) using a carbon paste electrochemical (CPE) modified with a porous material, such as natural phosphate (NP), was proposed. Adenosine strongly adsorbed on a electrode surface and prepared electrode NP-CPE provides easy methods for the detection of low concentrations of extracellular adenosine using cyclic voltammetry (cv) and square wave voltammetry (swv). Some electrochemical properties, in particular the influence of pH, the effect of the electrolyte have been studied. The elaborate electrode was then subjected to an analytical application for the detection of extracellular adenosine in serum. Keywords: Adenosine, Cyclic voltammogram, Square wave voltammogram, CPE, NP