Synthesis of Novel Thiazoles Based on (+)-Usnic Acid
Aleksandr S. Filimonov,
Olga A. Luzina,
Nariman F. Salakhutdinov
Affiliations
Aleksandr S. Filimonov
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9, Lavrentieva Ave., 630090 Novosibirsk, Russia
Olga A. Luzina
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9, Lavrentieva Ave., 630090 Novosibirsk, Russia
Nariman F. Salakhutdinov
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9, Lavrentieva Ave., 630090 Novosibirsk, Russia
A series of usnic acid derivatives containing a thiazole ring with an amide substituent were synthesized. The convenient method for synthesis of these compounds is a reaction of 14-bromousnic acid with N-acylthioureas. Acylation of aminothiazole does not lead to the targeted compound.